Results 271 to 280 of about 129,162 (296)

Familial Primary Progressive Aphasia

Alzheimer Disease & Associated Disorders, 2003
Primary progressive aphasia (PPA) is a neurodegenerative disease presenting with isolated, progressive, language dysfunction. After at least 2 years, dementia may develop, but the aphasia predominates. Few families with hereditary PPA have been reported; some have autosomal dominance. A chromosome 17 mutation in tau exon 13 has been found in one family,
Thomas A, Krefft, Neill R, Graff-Radford, Dennis W, Dickson, Matt, Baker, Rudy J, Castellani   +4 more
openaire   +2 more sources

The affective, behavioural, and cognitive reactions to a diagnosis of Primary Progressive Aphasia: A qualitative descriptive study

Dementia, 2022
Objectives Receiving a diagnosis of neurodegenerative disorder is life changing. Primary progressive aphasia is one such disease. Understanding how receiving this diagnosis impacts on individuals may help plan support services.
K. Lo, Geraldine Bricker-Katz, K. Ballard, O. Piguet   +3 more
semanticscholar   +1 more source

Primary progressive aphasia

Annals of Neurology, 2001
AbstractPrimary progressive aphasia (PPA) is a focal dementia characterized by an isolated and gradual dissolution of language function. The disease starts with word‐finding disturbances (anomia) and frequently proceeds to impair the grammatical structure (syntax) and comprehension (semantics) of language.
openaire   +2 more sources

Non-pharmacological interventions for improving language and communication in people with primary progressive aphasia.

Cochrane Database of Systematic Reviews
BACKGROUND Primary progressive aphasia (PPA) accounts for approximately 43% of frontotemporal dementias and is mainly characterised by a progressive impairment of speech and communication abilities.
M. Roheger, Steffen Riemann, Andreas Brauer, Ellen McGowan, Ulrike Grittner, A. Flöel, M. Meinzer   +6 more
semanticscholar   +1 more source

An international core outcome set for primary progressive aphasia (COS‐PPA): Consensus‐based recommendations for communication interventions across research and clinical settings

Alzheimer's & Dementia
Interventions to treat speech‐language difficulties in primary progressive aphasia (PPA) often use word accuracy as a highly comparable outcome. However, there are more constructs of importance to people with PPA that have received less attention.
A. Volkmer, E. Alves, H. Bar-Zeev, Elena Barbieri, Petronilla Battista, A. Beales, B. Beber, Emilie V Brotherhood, Inês Cadório, M. T. Carthery-Goulart, J. Cartwright, Sebastian Crutch, K. Croot, Maria Isabel d´Ávila Freitas, J. Gallée, Stephanie M Grasso, Katarina L Haley, Heleen M. A. Hendriksen, Shalom K Henderson, L. Jiskoot, Isabel Junqueira Almeida, J. Kindell, R. Kingma, L. Kwan-Chen, Monica Lavoie, Adi Lifshitz-Ben-Basat, Regina Jokel, Aurore Mahut‐Dubos, Jordi A. Matias-Guiu, Michèle Masson-Trottier, M. Meinzer, Ellen McGowan, C. Méndez-Orellana, A. Meyer, Carly Millanski, N. Montagut, Aimee R Mooney, D. Morhardt, Lyndsey Nickels, Monica Norvik, I. Nowenstein, A. Paplikar, M. Pozzebon, A. Renard, L. Ruggero, Emily Rogalski, A. U. Rysop, Fredrik Sand Aronsson, Aida Suárez-González, Sharon A Savage, Mai Tran Thi, Kyriana Tsapkini, C. Taylor-Rubin, Donna C. Tippett, Nina Unger, Lizet van Ewijk, S. Wielaert, I. Winsnes, Anne Whitworth, İbrahim Can Yaşa, D. Copland, Maya L Henry, Jason D. Warren, Rosemary Varley, S. Wallace, Chris J D Hardy   +65 more
semanticscholar   +1 more source

Primary progressive aphasia presenting as conduction aphasia

Journal of the Neurological Sciences, 1999
We report a case of a woman with primary progressive aphasia (PPA) who presented with conduction aphasia. A 60-year-old, right-handed, Japanese female suffering from progressive aphasia had difficulty in repeating words and phrases. She displayed phonemic paraphasias but had preserved comprehension and had no cognitive or behavior disorder for more ...
K, Hachisuka, M, Uchida, Y, Nozaki, S, Hashiguchi, M, Sasaki   +4 more
openaire   +2 more sources

Primary progressive aphasia

Aphasiology, 1992
Abstract In recent years there has been increasing interest in individuals with gradual deterioration of language skills in the absence of generalized cognitive impairments or identifiable vascular, neoplastic, metabolic, or infectious aetiology. In this paper, we review the available data on primary progressive aphasia and summarize the demographic ...
Joseph R. Duffy, Ronald C. Petersen
openaire   +1 more source

Primary progressive aphasia

Neurology, 2010
When a patient presents with acute aphasia, today's neurologist takes swift action to characterize the clinical syndrome and use neuroimaging and other tools to identify its pathophysiologic basis. One goal of these urgent efforts is to determine whether the patient has an ischemic process that merits thrombolytic intervention.
openaire   +1 more source

Imaging in primary progressive aphasia

Neuroradiology, 1997
Primary progressive aphasia (PPA) presents with aphasia, with or without other minor cognitive dysfunction. We report five patients with PPA to show the correlation between their clinical signs and imaging findings. The patients can be divided into those with nonfluent (group 1) and those with fluent (group 2) aphasia.
K, Abe, H, Ukita, T, Yanagihara
openaire   +2 more sources

Primary progressive aphasia.

Clinical neuroscience (New York, N.Y.), 1997
Primary progressive aphasia is an important recently emphasized clinical syndrome that is a common early manifestation of Pick's disease and Pick complex pathology. It is defined clinically as slowly progressive language disturbance that remains relatively isolated from other cognitive or behavioral deficits for at least 2 years.
A, Kertesz, D G, Munoz
openaire   +1 more source