Results 21 to 30 of about 129,162 (296)

Genetic forms of primary progressive aphasia within the GENetic Frontotemporal dementia Initiative (GENFI) cohort: comparison with sporadic primary progressive aphasia

Brain Communications, 2023
Primary progressive aphasia is most commonly a sporadic disorder, but in some cases, it can be genetic. This study aimed to understand the clinical, cognitive and imaging phenotype of the genetic forms of primary progressive aphasia in comparison to the ...
K. Samra, A. Macdougall, A. Bouzigues, M. Bocchetta, D. Cash, C. Greaves, R. Convery, C. Hardy, J. V. van Swieten, H. Seelaar, L. Jiskoot, F. Moreno, R. Sánchez-Valle, R. Laforce, C. Graff, M. Masellis, M. Tartaglia, J. Rowe, B. Borroni, E. Finger, M. Synofzik, D. Galimberti, R. Vandenberghe, A. de Mendonça, Christopher R. Butler, A. Gerhard, S. Ducharme, I. Le Ber, I. Santana, F. Pasquier, J. Levin, M. Otto, S. Sorbi, J. Warren, J. Rohrer, L. Russell   +35 more
semanticscholar   +1 more source

Spared speech fluency is associated with increased functional connectivity in the speech production network in semantic variant primary progressive aphasia

Brain Communications, 2023
Semantic variant primary progressive aphasia is a clinical syndrome characterized by marked semantic deficits, anterior temporal lobe atrophy and reduced connectivity within a distributed set of regions belonging to the functional network associated with
M. Montembeault, Z. Miller, Amandine Géraudie, Peter S. Pressman, Antoine Slegers, Carly Millanski, Abigail E. Licata, Buddhika M Ratnasiri, M. Mandelli, M. Henry, Y. Cobigo, H. Rosen, B. Miller, S. Brambati, M. Gorno‐Tempini, Giovanni Battistella   +15 more
semanticscholar   +1 more source

Perspective of Speech and Language Therapists in Turkey on Primary Progressive Aphasia

SAGE Open, 2023
Primary progressive aphasia (PPA) is a neurodegenerative disease characterized by the insidious and progressive loss of speech and language skills. However, there is no standardized intervention method applied in patients with PPA.
İbrahim Can Yaşa
semanticscholar   +1 more source

Lexical markers of disordered speech in primary progressive aphasia and ‘Parkinson-plus’ disorders

medRxiv, 2023
Connected speech samples elicited by a picture description task are widely used in the assessment of aphasias, but it is not clear what their interpretation should focus on.
Shalom K Henderson, S. Ramanan, Karalyn E Patterson, Peter Garrard, Nikil Patel, Katie A. Peterson, A. Halai, Stefano F Cappa, James B. Rowe, M. L. Lambon Ralph   +9 more
semanticscholar   +1 more source

Using the Medical Research Council framework and public involvement in the development of a communication partner training intervention for people with primary progressive aphasia (PPA): Better Conversations with PPA

BMC Geriatrics, 2021
Background Primary progressive aphasia is a language-led dementia resulting in a gradual dissolution of language. Primary progressive aphasia has a significant psychosocial impact on both the person and their families.
Anna Volkmer, Aimee Spector, Kate Swinburn, Jason D. Warren, Suzanne Beeke   +4 more
doaj   +1 more source

Structural correlates of language processing in primary progressive aphasia

Brain Communications, 2023
Understanding the relationships between brain structure and language behaviour in primary progressive aphasia provides crucial information about these diseases’ pathomechanisms.
Curtiss A. Chapman, M. Polyakova, Karsten Mueller, C. Weise, K. Fassbender, K. Fliessbach, J. Kornhuber, M. Lauer, S. Anderl-Straub, A. Ludolph, J. Prudlo, A. Staiger, M. Synofzik, J. Wiltfang, L. Riedl, J. Diehl-Schmid, M. Otto, A. Danek, G. Hartwigsen, M. Schroeter   +19 more
semanticscholar   +1 more source

Principles and philosophies for speech and language therapists working with people with primary progressive aphasia: an international expert consensus

Disability and Rehabilitation, 2022
Purpose Primary progressive aphasia (PPA) is a language-led dementia associated with Alzheimer’s pathology and fronto-temporal lobar degeneration. Multiple tailored speech and language interventions have been developed for people with PPA.
A. Volkmer, J. Cartwright, L. Ruggero, A. Beales, J. Gallée, S. Grasso, M. Henry, R. Jokel, J. Kindell, R. Khayum, M. Pozzebon, E. Rochon, C. Taylor-Rubin, R. Townsend, F. Walker, S. Beeke, D. Hersh   +16 more
semanticscholar   +1 more source

Feasibility study of Internet video-based speech-language activity for outpatients with primary progressive aphasia.

PLoS ONE, 2023
BackgroundPrimary progressive aphasia is a clinical dementia syndrome secondary to neurodegenerative disease characterized by language-related difficulties. Currently, there is no effective treatment for language impairment in primary progressive aphasia.
Shinji Higashi, Yuko Koshibe, Takehiro Miyazaki, Ryohei Watanabe, Hanako Nakanome, Takeshi Inoue, Takashi Asada, Tetsuaki Arai   +7 more
doaj   +1 more source

White matter disease correlates with lexical retrieval deficits in primary progressive aphasia

Frontiers in Neurology, 2013
Objective: To relate fractional anisotropy changes associated with the semantic and logopenic variants of primary progressive aphasia to measures of lexical retrieval.Methods: We collected neuropsychological testing, volumetric MRI, and diffusion ...
John P. Powers, Corey T. McMillan, Caroline C. Brun, Paul A. Yushkevich, Hui eZhang, James C. Gee, Murray eGrossman   +6 more
doaj   +1 more source

Use of transcranial magnetic stimulation in the treatment of nonfluent primary progressive aphasia: a case report [PDF]

Dementia & Neuropsychologia, 2023
Primary progressive aphasia comprises a group of neurodegenerative diseases characterized by progressive speech and language dysfunction. Neuroimaging (structural and functional), biomarkers, and neuropsychological assessments allow for early diagnosis ...
Natália Maria Lins Martins, Tathiana Baczynski, Larissa Sena, Romário de Macedo Espíndola, Natia Horato, Antonio Egidio Nardi, Valeska Marinho   +6 more
doaj   +1 more source