Results 81 to 90 of about 4,995,796 (238)

ATP Citrate Lyase in Metabolic Disease: Mechanistic Insights and Clinical Potential

iNew Medicine, EarlyView.
ATP citrate lyase (ACLY) is a central metabolic hub that diverts mitochondrial citrate to fuel de novo lipogenesis, cholesterol biosynthesis, and protein acetylation. Given its robust correlation with pathological changes in multiple human diseases, ACLY inhibitors featuring distinct pharmacological strengths have been developed for therapeutic ...
Wenbiao Wang, Xinyan Li, Honglu Shi, Gaolei Song, Zhifu Xie, Jingya Li   +5 more
wiley   +1 more source

Protective Role of Polydatin Against Vancomycin‐Induced Lung Toxicity via Oxidative Stress, Inflammation, Endoplasmic Reticulum Stress, Apoptosis, and Ferroptosis Pathways

Journal of Applied Toxicology, EarlyView.
ABSTRACT This study aimed to evaluate whether polydatin (Poly) could eliminate the harmful effects of vancomycin (VCM) on the lungs of rats. Rats were administered VCM (200 mg/kg) and Poly (50 mg/kg), both separately and in combination, for a duration of 7 days.
Serpil Aygörmez, Sefa Küçükler, Selim Çomaklı, Hasan Şimşek, Özge Kandemir, Fatih Mehmet Kandemir, Şaban Maraşlı   +6 more
wiley   +1 more source

A case of primary pulmonary NK/T cell lymphoma presenting as pneumonia

Respiratory Medicine Case Reports, 2016
Primary pulmonary lymphoma, particularly non-B cell lymphomas involving lung parenchyma, is very rare. A 46-year-old male was admitted to the hospital with fever and cough. Chest X-ray showed left lower lobe consolidation, which was considered pneumonia.
Sangho Lee, Bongkyung Shin, Hyungseok Yoon, Jung Yeon Lee, Gyu Rak Chon   +4 more
doaj   +1 more source

Biochemical and Molecular Insights Into Monocrotaline‐Induced Hepatotoxicity: An Experimental Mouse Study

Journal of Applied Toxicology, EarlyView.
ABSTRACT Monocrotaline (MCT), a plant‐derived pyrrolizidine alkaloid, is well known for its hepatotoxic effects. However, full elucidation of the mechanisms underlying MCT‐induced hepatotoxicity, as well as the development of reliable biomarkers for early detection and monitoring, requires an integrated evaluation of biochemical, molecular, and ...
Ali Şenol, Alparslan Kadir Devrim, Miyase Çinar, Mahmut Sözmen, Fatma Betül Akça   +4 more
wiley   +1 more source

Primary pulmonary AIDS-related lymphoma

, 2005
Extranodal involvement is common in lymphomas associated with human immunodeficiency virus infection (HIV) and acquired immunodeficiency syndrome (AIDS).
Schtirbu, Ricardo, Trione, Norberto, Narbaitz, Marina, Villafañe, María F., Corti, Marcelo   +4 more
core  

Research Progress of Pulmonary Extranodal Marginal Zone Lymphoma

Chinese Journal of Lung Cancer
Mucosa-associated lymphoid tissue (MALT) lymphoma is the most common primary pulmonary lymphoma, which is an indolent B-cell lymphoma thought to originate from marginal zone B cells. Its pathophysiology is closely related to chronic antigenic stimulation,
Shaowei ZHANG
doaj   +1 more source

Pulmonary diffuse large B-cell lymphoma with concurrent organizing pneumonia: a case report

Frontiers in Medicine
Primary pulmonary lymphoma represents an uncommon extranodal manifestation of non-Hodgkin lymphoma, with atypical clinical and radiographic features frequently leading to diagnostic challenges.
Xiaofeng Lu, Dekun Zhou, Li Zou, Guoqi Zhou   +3 more
doaj   +1 more source

Primary pulmonary lymphoma in Peru. [PDF]

Ecancermedicalscience, 2023
Requena EDA, Ocrospoma DV, Ruiz JS, De la Guerra Pancorvo A, Kajatt EA.   +4 more
europepmc   +1 more source

Nail Disorders in Systemic Conditions

JEADV Clinical Practice, EarlyView.
ABSTRACT Nail findings in children can be indicative of an underlying systemic disease. Many of these findings are seen in multiple entities and are not specific to one disease. The importance of specifically examining for these nail changes cannot be overstated.
Jane Sanders Bellet
wiley   +1 more source

Primary Pulmonary Non-Hodgkin’s Lymphoma: A Case Report and Literature Review

Chinese Journal of Lung Cancer, 2011
Primary pulmonary non-Hodgkin’s lymphoma (PPNHL) is a kind of malignant lymphoma originated from lymphoid tissue of the lung. PPNHL is a rare type in extra nodal lymphoma.
Yong LIANG, Rong FU, Shan GAO, Xifeng DONG, Zonghong SHAO   +4 more
doaj   +1 more source