Results 101 to 110 of about 10,933,254 (364)
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
Exploring personality traits and well-being among pre-school and primary school teachers in Croatia
Current Issues in Personality Psychology, 2017 Background Pre-school and primary school teachers are directly involved in the education of children. In addition to teachers’ competences, the quality of their work is significantly influenced by their psychological well-being.
Sanja Tatalović Vorkapić, Irena Peloza
doaj +1 more source
International Journal of Behavioral Nutrition and Physical Activity, 2015 BackgroundHealthy eating by primary school-aged children is important for good health and development. Schools can play an important role in the education and promotion of healthy eating among children.
Dean Dudley, W. Cotton, L. Peralta
semanticscholar +1 more source
FEBS Letters, EarlyView.Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson +7 more
wiley +1 more source
The importance of English in primary school education in China: perceptions of students
, 2016 English has become a compulsory subject from Primary Three in China since 2003 and is gradually being introduced even earlier into the curriculum in many schools.
G. Qi
semanticscholar +1 more source
PLoS ONE, 2015 Objective Teachers' attitudes toward inclusion are often based on the practical implementation of inclusive education rather than a specific ideology and understanding of inclusiveness.
S. Vaz +6 more
semanticscholar +1 more source
Molecular Oncology, EarlyView.AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou +5 more
wiley +1 more source
Molecular Oncology, EarlyView.A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira +14 more
wiley +1 more source
Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids
Molecular Oncology, EarlyView.This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici +8 more
wiley +1 more source
Teaching English at Primary School
Nobel: Journal of Literature and Language Teaching, 2017 There is a fear that teaching foreign language to primary school students may distract the growth of nationalism feeling of the students. It is due to the fact that children within 6 to 12 years old are vulnerable.
Diah Ikawati Ayuningtias
doaj +1 more source