Results 151 to 160 of about 3,665,788 (354)
Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib
Molecular Oncology, EarlyView.WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute +17 more
wiley +1 more source
Molecular Oncology, EarlyView.The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg +43 more
wiley +1 more source
Proposition of Primary School Students’ Poetry
Jurnal Pendidikan Humaniora, 2015 Proposisi Puisi Karya Anak Sekolah Dasar Abstract: Proposition can be utilized for reviewing schemata and language skills of children, either in the form of a sentence or the linnes of poetry. Arguments and predication (proposition’s content) in poetry by children shows logical relationship, with associative relationship and or colocative.
Rizka Amaliah +2 more
openaire +1 more source
Effective pre-school, primary and secondary education project (EPPSE 3-14): students’ reports of their experiences of school in Year 9 [PDF]
, 2011 The Effective Pre-school, Primary and Secondary Education Project (EPPSE) has inves tigated the academic and social behavioural (+ in the later stages the affective) development of approximately 3,000 children from the age of 3+ years since 1997.
Draghici, D. +7 more
core +2 more sources
Molecular Oncology, EarlyView.We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala +15 more
wiley +1 more source
Examining Roma Primary School Students' Expectations From School
Revista de Gestão Social e AmbientalObjective: The aim of this study is to reveal what the expectations of Roma primary school students residing in Doğanlar Neighborhood in Konya are from school. Theoretical Framework: The basis of this research is the expectations of Roma students from school. There are not many studies on Roma students in the literature. This research is important
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Minimization of Illness Absenteeism in Primary School Students Using Low-Cost Hygiene Interventions [PDF]
, 2012 Objective: Safe water and hygiene intervention was evaluated to assess its impact on students’ health, hygiene practices and reduction in illness absenteeism in primary school students.
Shirsat, SD, Tambekar, DH
core
Molecular Oncology, EarlyView.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
TRAINING PRIMARY SCHOOL TEACHERS FOR EDUCATING HUMANITY OF PRIMARY SCHOOL STUDENTS
Humanities science current issues, 2023 Lyubov KANISHEVSKA, Angelika LESYK
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Primary School Students' Perceptions of Technology
Malaysian Online Journal of Educational Technology, 2018 It was aimed with this study to identify primary school fourth-grade students' perceptions of technology. The study was designed as phenomenology method. The participants of the research were composed of 58 primary school fourth-grade students attending to a public school.
openaire +1 more source