Results 161 to 170 of about 3,665,788 (354)

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Akin to my teacher: Does caste, religious or gender distance between student and teacher matter? Some evidence from India [PDF]

open access: yes
This paper uses a unique data set from 5028 primary school children in rural India to examine whether the demographic interactions between students and teachers influence student outcomes and whether social distance between student and teacher ...
Geeta Kingdon, Shenila Rawal
core  

Kesiapan Memasuki Sekolah Dasar pada Anak di Tkit Attaqwa Gumawang Tahun 2016 [PDF]

open access: yes, 2017
Education becomes an essential thing in human development and nation progress. Phenomenon of elementary school test that should become an interesting thing, is a new scourge for students and parents.
Andriani, D. (Dwi)   +2 more
core  

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

open access: yesMolecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta   +10 more
wiley   +1 more source

Signaling the Competencies of High School Students to Employers [PDF]

open access: yes, 1994
[Excerpt] The fundamental cause of the low effort level of American students, parents, and voters in school elections is the absence of good signals of effort and accomplishment and the consequent lack of rewards for learning.
Bishop, John H.
core   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

The Impacts of Retention, Expenditures, and Class Size on Primary School Completion in Sub-Saharan Africa: A Cross-National Analysis

open access: yesInternational Journal of Education Policy and Leadership, 2016
Education in Sub-Saharan Africa is increasingly viewed as a means of emancipation and a transformative project for social mobility. Developing nations have pursued policies such as universal or free primary education to increase access to education and ...
Ryan Richard Ruff
doaj  

Early College, Early Success: Early College High School Initiative Impact Study [PDF]

open access: yes, 2013
In 2002, the Bill & Melinda Gates Foundation launched the ECHSI with the primary goal of increasing the opportunity for underserved students to earn a postsecondary credential.
Andrea Berger   +11 more
core  

RIPK4 function interferes with melanoma cell adhesion and metastasis

open access: yesMolecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski   +9 more
wiley   +1 more source

Participation Status of Primary School Students

open access: yesProcedia - Social and Behavioral Sciences, 2015
AbstractIn this study, the aim was to determine participation status of primary school students at school, in the family and in society. Research sample was composed of 348 students studying at the 6th, 7th and 8th grades in a primary school in Kırşehir which is found in the Central Anatolia Region of Turkey. In the research, data collection tool named
openaire   +1 more source

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