Results 151 to 160 of about 2,309,457 (305)

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata   +10 more
wiley   +1 more source

Realistic Mathematics Education Model for Logical Reasoning of Primary Students

open access: yesJurnal Math Educator Nusantara: Wahana Publikasi Karya Tulis Ilmiah di Bidang Pendidikan Matematika
Logical reasoning for primary school students is still relatively low. Meanwhile, primary school students need logical reasoning to solve problems based on reasonable facts.
Reza Aulia Windari   +1 more
doaj   +1 more source

Bilingual behaviour checklists: initiating a student, teacher and parent partnership in behaviour management. [PDF]

open access: yes, 2001
Three bilingual (Maori and English) behavioural checklists formed part of a project designed to facilitate student, teacher and whanau collaboration in overcoming behavioural difficulties experienced by Maori students, (Hei Awhina Matua).
Atvars, Kathryn   +4 more
core   +1 more source

Participation Status of Primary School Students

open access: yesProcedia - Social and Behavioral Sciences, 2015
AbstractIn this study, the aim was to determine participation status of primary school students at school, in the family and in society. Research sample was composed of 348 students studying at the 6th, 7th and 8th grades in a primary school in Kırşehir which is found in the Central Anatolia Region of Turkey. In the research, data collection tool named
openaire   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

Using Discourse Analysis Methodology to Teach Legal English [PDF]

open access: yes, 2011
In this study, I propose a curriculum focused on raising students’ linguistic awareness through rigorous discourse analysis and reflective writing in a legal context.
Hoffman, Craig
core   +1 more source

DNA methylation and expression of MAPRE3 affect overall survival of early‐stage non‐small cell lung cancer patients

open access: yesMolecular Oncology, EarlyView.
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen   +14 more
wiley   +1 more source

Internet Usage Experiences of Primary School Students: A Phenomenological Study

open access: yesHayef: Journal of Education, 2023
Uğur GÜNEL , Naif ERGÜN
doaj   +1 more source

A Field View of Soil - Digging Around [PDF]

open access: yes, 2003
The purpose of this resource is to understand that variations in landscape can affect soil properties. Students investigate variations in the soils around their school to discover that soil properties like moisture and temperature exhibit considerable ...
The GLOBE Program, University Corporation for Atmospheric Research (UCAR)
core  

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

open access: yesFEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li   +8 more
wiley   +1 more source

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