Results 61 to 70 of about 396,045 (311)
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
Health and Social Care Delivery ResearchBackground Remote services (in which the patient and staff member are not physically colocated) and digital services (in which a patient encounter is digitally mediated in some way) were introduced extensively when the COVID-19 pandemic began in 2020. We
Trisha Greenhalgh +22 more
doaj +1 more source
Jaundice in primary school pupils [PDF]
Postgraduate Medical Journal, 2002 Answers on p 59. A previously well 10 year old boy was admitted from school with increasing epigastric pain and vomiting. He had a six day history of feeling generally unwell and feverish with loose motions. On examination he was well, pyrexial at …
I, Stephenson +3 more
openaire +2 more sources
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
FEBS Letters, EarlyView.Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
Early professional development and languages teaching in primary schools: Case studies of teachers trained on an employment based route [PDF]
, 2013 This article describes an Escalate-funded research project, which investigated the professional development of new primary teachers, trained on employment-based routes, in teaching modern foreign languages (MFL).
Manuela Thomae (6117164) +3 more
core +1 more source
The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
FEBS Letters, EarlyView.Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source
Peer Effects in European Primary Schools: Evidence from PIRLS [PDF]
We estimate peer effects for fourth graders in six European countries. The identification relies on variation across classes within schools. We argue that classes within primary schools are formed roughly randomly with respect to family background ...
Pischke, Jörn-Steffen +1 more
core +2 more sources
Digital libraries at home and abroad for the needs of instruction in the school library
Knjižnica, 2001 The authors describe some cases and indicate some possible uses of digital libraries (some of them can also be examples of their construction) for educational purposes, at home and abroad.
Zdenka Verlič
doaj +1 more source
Researching the Arts in Primary Schools [PDF]
This major report details the findings of the RAPS (Researching the Arts in Primary Schools) project. This three-year project on arts-rich schools sought to discover the characteristics of arts-rich schools.
Hall, Christine +2 more
core
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source