Results 301 to 310 of about 62,620 (348)

Primary sclerosing cholangitis

Lancet, The, 2018
Primary sclerosing cholangitis is a rare, chronic cholestatic liver disease characterised by intrahepatic or extrahepatic stricturing, or both, with bile duct fibrosis. Inflammation and fibrosis of bile ducts and the liver are followed by impaired bile formation or flow and progressive liver dysfunction.
Jessica K Dyson, Ulrich Beuers, David E J Jones   +2 more
exaly   +4 more sources

The microbiota and the gut–liver axis in primary sclerosing cholangitis

Nature Reviews Gastroenterology and Hepatology, 2022
Johannes Roksund Hov, Tom H Karlsen
exaly   +2 more sources

Intestinal dysbiosis augments liver disease progression via NLRP3 in a murine model of primary sclerosing cholangitis

Gut, 2019
Objective There is a striking association between human cholestatic liver disease (CLD) and inflammatory bowel disease. However, the functional implications for intestinal microbiota and inflammasome-mediated innate immune response in CLD remain elusive.
Lijun Liao, Kai Markus Schneider, Hanns-Ulrich Marschall   +2 more
exaly   +2 more sources

Altered faecal microbiome and metabolome in IgG4-related sclerosing cholangitis and primary sclerosing cholangitis

Gut, 2021
Objective Multiple clinical similarities exist between IgG4-related sclerosing cholangitis (IgG4-SC) and primary sclerosing cholangitis (PSC), and while gut dysbiosis has been extensively studied in PSC, the role of the gut microbiota in IgG4-SC remains ...
Qiaoyan Liu, Bo Li, Yikang Li, Yiran Wei, Bingyuan Huang, Jubo Liang, Z. You, You Li, Qiwei Qian, Rui Wang, Jun Zhang, Ruiling Chen, Zhuwan Lyu, Yong Chen, M. Shi, Xiao Xiao, Qixia Wang, Q. Miao, J. Fang, M. Gershwin, M. Lian, Xiong Ma, R. Tang   +22 more
semanticscholar   +1 more source

Global incidence, prevalence and features of primary sclerosing cholangitis: A systematic review and meta‐analysis

Liver international (Print), 2021
Primary sclerosing cholangitis (PSC) is an idiopathic, cholestatic liver disease with a diverse range of clinical manifestations. Inter‐regional data on PSC are variable, but its global geoepidemiology has not been well‐studied.
T. Mehta, S. Weissman, Brian M. Fung, J. Sotiriadis, K. Lindor, J. Tabibian   +5 more
semanticscholar   +1 more source

Primary sclerosing cholangitis

The American Journal of Surgery, 1987
Primary sclerosing cholangitis was seen in only 7 of 6,494 biliary operations performed between 1948 and 1979. Fifteen more cases were seen in 1,467 biliary operations performed over a recent 5 year period. Surgery was directed primarily towards the differential diagnosis between cholangiocarcinoma and primary sclerosing cholangitis of the upper bile ...
T T, White, M J, Hart
openaire   +4 more sources

Primary sclerosing cholangitis

Current Treatment Options in Gastroenterology, 2001
There is no proven medical therapy for primary sclerosing cholangitis. The goal of management should be treatment of symptoms and complications of cholestasis, as well as attempts at treating the underlying disease process. In addition, efforts should be made to recognize and treat or prevent the known complications of primary sclerosing cholangitis ...
Young-Mee, Lee, David J., Kim
openaire   +2 more sources

Primary Sclerosing Cholangitis

Endoscopy, 1985
Primary sclerosing cholangitis was diagnosed in 6 patients (4 men and 2 women), with ages ranging from 33 to 71 years. Four of them had ulcerative colitis, with an evolution from 8 to 21 years, the other two had Crohn's disease with 2 and 3 years of evolution.
A D, Jorge, C, Esley
openaire   +4 more sources