Results 41 to 50 of about 39,460 (147)

Alterations of the bile microbiome in primary sclerosing cholangitis

Gut, 2019
Background Patients with primary sclerosing cholangitis (PSC) display an altered colonic microbiome compared with healthy controls. However, little is known on the bile duct microbiome and its interplay with bile acid metabolism in PSC.
T. Liwinski, R. Zenouzi, C. John, H. Ehlken, M. Rühlemann, C. Bang, S. Groth, W. Lieb, M. Kantowski, Nils Andersen, G. Schachschal, T. Karlsen, J. Hov, T. Rösch, A. Lohse, J. Heeren, A. Franke, C. Schramm   +17 more
semanticscholar   +1 more source

Review of primary sclerosing cholangitis with increased IgG4 levels

World Journal of Gastroenterology, 2020
Primary sclerosing cholangitis (PSC) is a chronic progressive liver disease. Sub-types of PSC have been described, most recently PSC with elevated serum and/or tissue IgG4 subclass.
C. Manganis, R. Chapman, E. Culver
semanticscholar   +1 more source

Hepatobiliary manifestations in inflammatory bowel disease: The gut, the drugs and the liver [PDF]

, 2013
Abnormal liver biochemical tests are present in up to 30% of patients with inflammatory bowel disease (IBD), and therefore become a diagnostic challenge.
Ampuero Herrojo, Javier, Castro Fernández, Manuel, Rojas Feria, María, Romero Gómez, Manuel, Suárez, Emilio   +4 more
core   +1 more source

Analysis of IL2/IL21 Gene Variants in Cholestatic Liver Diseases Reveals an Association with Primary Sclerosing Cholangitis [PDF]

, 2011
Background/Aims: The chromosome 4q27 region harboring IL2 and IL21 is an established risk locus for ulcerative colitis (UC) and various other autoimmune diseases.
Albers HM, Barrett JC, Barrett JC, Bergquist A, Bergquist A, Bo X, Burkhard Göke, Chapman R, Chen B, Christian Rust, Daha NA, Fay MP, Festen EA, Gerald Ulrich Denk, Gershwin ME, Gershwin ME, Glas J, Glas J, Henckaerts L, Hinks A, Hirschfield GM, Johannes Stallhofer, Jürgen Glas, Kaplan MM, Karlsen TH, Laurence A, Li Y, Liu Y, Loftus, Loftus EV, Maiti AK, Malek TR, Marquez A, McGuire HM, Peluso I, Rüdiger Paul Laubender, Saarinen S, Sadlack B, Saich R, Saraiva M, Sawalha AH, Sgouroudis E, Stephan Brand, Thomas Pusl, Todd JA, van Heel DA, Weismuller TJ, Yamanouchi J, Yang L, Zheng SG, Zhernakova A, Zhernakova A   +51 more
core   +1 more source

Effect of liver transplantation on inflammatory bowel disease in patients with primary sclerosing cholangitis [PDF]

, 2002
This report investigates the influence of liver transplantation and concomitant immunosuppression on the course of progression of inflammatory bowel disease (IBD) and discusses statistical methodology appropriate for such settings.
A. Jake Demetris, Abu-Elmagd, Befeler, Bleday, Brentnall, Chapman, Cottone, D'Haens, Fellermann, Gavaler, Greenstein, Hanauer, Higashi, Ierardi, Igor Dvorchik, John J. Fung, Kareem M. Abu-Elmagd, Katzka, Knechtle, Lichtiger, Loftus, Lowry, Michael Subotin, Miki, Narumi, Papatheodoridis, Papatheodoridis, Present, Rennick, Sahai, Samuel Wieand, Shaked, Stephens, Thomas E. Starzl   +33 more
core   +1 more source

Serum Metabolites as Diagnostic Biomarkers for Cholangiocarcinoma, Hepatocellular Carcinoma, and Primary Sclerosing Cholangitis

Hepatology, 2019
Early and differential diagnosis of intrahepatic cholangiocarcinoma (iCCA) and hepatocellular carcinoma (HCC) by noninvasive methods represents a current clinical challenge.
J. Banales, M. Iñarrairaegui, A. Arbelaiz, P. Milkiewicz, J. Muntané, L. Muñoz-Bellvís, A. La Casta, Luis M. Gónzalez, Enara Arretxe, C. Alonso, I. Martínez‐Arranz, A. Lapitz, A. Santos-Laso, M. Ávila, M. Martínez‐Chantar, L. Bujanda, J. Marin, B. Sangro, R. Macías   +18 more
semanticscholar   +1 more source

A Common Variant in CLDN14 is Associated with Primary Biliary Cirrhosis and Bone Mineral Density. [PDF]

, 2016
Primary biliary cirrhosis (PBC), a chronic autoimmune liver disease, has been associated with increased incidence of osteoporosis. Intriguingly, two PBC susceptibility loci identified through genome-wide association studies are also involved in bone ...
Bian, Zhaolian, Chen, Haoyan, Gershwin, M Eric, Jiang, Xiang, Li, Enling, Li, Zhiqiang, Lian, Min, Liao, Wilson, Ma, Xiong, Miao, Qi, Seldin, Michael F, Shi, Yongyong, Tang, Ruqi, Wang, Qixia, Wang, Zhaoyue, Wei, Yiran, Yang, Fan, Yang, Yue, Zhang, Haiyan   +18 more
core   +2 more sources

Cancer risk in primary sclerosing cholangitis: Epidemiology, prevention, and surveillance strategies

World Journal of Gastroenterology, 2019
Primary sclerosing cholangitis (PSC) is a rare cholestatic liver disease characterized by progressive fibroinflammatory destruction of the intra- and/or extrahepatic biliary ducts. While its features and disease course can be variable, most patients with
Brian M. Fung, K. Lindor, J. Tabibian
semanticscholar   +1 more source

Intrahepatic bile duct strictures after human orthotopic liver transplantation - Recurrence of primary sclerosing cholangitis or unusual presentation of allograft rejection? [PDF]

, 1988
One of 55 patients transplanted for sclerosing cholangitis during the cyclosporin-steroid era (March 1980-June 1986) developed intrahepatic biliary strictures in the absence of allograft rejection within the 1st year posttransplantation.
A. C. Stieber, A. J. Demetris, AJ Demetris, B Portmann, C. O. Esquivel, J Lerut, J Neuberger, J. Lerut, J. W. Marsh, JW Marsh, KA Porter, R. D. Gordon, RH Fennell, S Iwatsuki, S. Iwatsuki, T. E. Starzl, TE Starzl   +16 more
core   +1 more source

Primary sclerosing cholangitis and inflammatory bowel disease comorbidity: an update of the evidence

Annals of gastroenterology : quarterly publication of the Hellenic Society of Gastroenterology, 2019
Comorbid primary sclerosing cholangitis (PSC) and inflammatory bowel disease (IBD) represent a unique disease phenotype with a different risk profile than PSC or IBD alone.
Andrew T. Mertz, N. Nguyen, K. Katsanos, R. Kwok   +3 more
semanticscholar   +1 more source