Results 111 to 120 of about 8,186,425 (263)
Unlocking the potential of cell‐permeable nanobodies for intracellular applications
FEBS Letters, EarlyView.This review outlines current strategies for delivery of nanobodies into cells and highlights recent examples of functional applications. By addressing and manipulating intracellular targets, these molecules hold great potential for treating cancer, respiratory diseases and neurological disorders, making this a vibrant area of research in the biomedical
Mariona Gené‐Verdés +2 more
wiley +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
The Influence of Implant Placement Angulation on Biomechanical Stability In Vitro Study
Journal of Pharmacy and Bioallied SciencesBackground: The angulation of dental implants significantly impacts their biomechanical stability, which plays a crucial role in the long-term success of implant therapy.
Piyush Javiya +6 more
doaj +1 more source
Brazil : Stability for Growth and Poverty Reduction
, 2003 The importance of macroeconomic stability for growth, and poverty reduction is now accepted in Brazil. As of 1964, the country followed responsible macroeconomic policies, in the pursuit of stability ...
World Bank
core +1 more source
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Effect of the Implant Length on its Primary Stability
, 2009 Dental implantology is one of the fastest developing areas of stomatology. An implantologists needs to have good quality medically proven information so that they can provide the best care for the patience from what today's science and market offers ...
L. Čapek, L. Dzan
core
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
Revista de la Asociación Odontológica Argentina, 2014 Resumen Objetivo: En ciertas situaciones clínicas, puede ser necesario cambiar la orientación del sensor Osstell ISQ™, pero se desconocen los efectos de dicha modificación.
María Constanza ibañez +2 more
doaj
Primary Implant Stability: A Crucial Pillar in Implantology
A good implant integration and long-term favourable clinical outcome are positively correlated with a secure primary (mechanical) stability of the implant. Consequently, in order to guarantee a successful osseointegration, it is ...
Aras, Meena A +4 more
core
Molecular Oncology, EarlyView.RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source