Results 101 to 110 of about 217,641 (208)

Commentary: The missing sabertooth baculum—At what point might the absence of evidence reasonably be considered evidence of absence?

The Anatomical Record, EarlyView.
Abstract Most carnivorans and all modern felids have ossified bacula; however, no machairodont baculum has ever been identified. This is true despite the many fairly complete skeletons found around the world of several sabertooth taxa. Although the bacula of modern felids are much smaller than those of canoids (even the least weasel's baculum is longer
Adam Hartstone‐Rose
wiley   +1 more source

China shares fossil treasures with the world

The Anatomical Record, EarlyView.
Abstract China has been a rich source of fossils for nearly a century, beginning with the discovery of so‐called Peking man (Sinanthropus pekinensis), known today as Homo erectus pekinensis in the mid 1920s. The first Chinese dinosaurs were described in 1929, the sauropod Helopus (now Euhelopus) and the ornithopod Tanius, described by the Swedish ...
Peter Dodson
wiley   +1 more source

Exploring the landscape of GenAI and education literature: A taxonomy of themes and sub‐themes

British Educational Research Journal, EarlyView.
Abstract The research landscape surrounding Generative Artificial Intelligence (GenAI) and education is rapidly expanding, characterised by a dynamic array of themes and sub‐themes. This paper aims to construct a comprehensive taxonomy that categorises the current literature on the integration of GenAI in educational settings.
Sam Clarke
wiley   +1 more source

Nanostructured drug delivery systems for posterior segment eye diseases: Strategies to defy ocular barriers

BMEMat, EarlyView.
Efficient drug delivery to the posterior segment of the eye has long been a challenging issue due to the complex ocular barriers. The review focuses on the promise held by nanoplatforms for barrier penetration and the key mechanisms involved, also highlighting their advantages in achieving efficient drug delivery and superior treatment of PSEDs ...
Yifan Shen, Ying Yao, Yan Zhang, Xinyu Shi, Ling Bai, Yang Zhong, Yan Zhang, Kun Zhang   +7 more
wiley   +1 more source

Development of Carborane‐Based Halogenated Naphthyridinone‐Analoga as Cannabinoid Receptor Type 2 (CB2R) Ligands

ChemMedChem, Accepted Article.
The cannabinoid receptor type 2 (CB2R) is overexpressed under pathological conditions. PET is a suitable non‐invasive imaging technique for diagnosing disease states, but requires a radiotracer that binds to CB2R with high affinity and selectivity. Currently, there is no suitable candidate routinely used in the clinics.
Lea Ueberham, Winnie Deuther-Conrad, Peter Lönnecke, Aleksandr Kazimir, Evamarie Hey-Hawkins   +4 more
wiley   +1 more source

Human behavior and human performance: Psychomotor demands [PDF]

The results of several experiments are presented in abstract form. These studies are critical for the interpretation and acceptance of flight based science to be conducted by the Behavior and Performance project. Some representative titles are as follow:

core   +1 more source

Confirmation of Fixed Quarterly Riliprubart Regimen in Patients with Cold Agglutinin Disease Using Population PK/PD and Exposure‐Response Analyses

Clinical Pharmacology &Therapeutics, EarlyView.
Riliprubart is a second‐generation, humanized immunoglobulin G4 that inhibits only the activated form of the C1s component of the proximal classical complement pathway. The clinical studies of riliprubart conducted thus far for the treatment of cold agglutinin disease (CAD), a rare autoimmune disease, include a Phase 1 first‐in‐human study in healthy ...
Timothy Chow, Marek Wardecki, Michael Storek, Nancy Wong   +3 more
wiley   +1 more source

Rodent monocyte‐derived macrophages do not express CD163: Comparative analysis using macrophages from living boreoeutherians

Developmental Dynamics, EarlyView.
Abstract Background CD163 is a scavenger receptor predominantly expressed on the surfaces of macrophages in various mammalian species and is a marker of anti‐inflammatory (M2‐like) macrophages. High density of CD163‐positive tumor‐associated macrophages (TAMs) is associated with worse prognosis in various patient tumors.
Yoichi Saito, Yukio Fujiwara, Yasuka L. Yamaguchi, Satomi S. Tanaka, Kyoko Miura, Yoshiyuki Hizukuri, Kyoko Yamashiro, Yasuhiro Hayashi, Yuta Nakashima, Yoshihiro Komohara   +9 more
wiley   +1 more source

Moving towards better risk assessment for invertebrate conservation

Ecography, EarlyView.
Global change threatens a vast number of species with severe population declines or even extinction. The threat status of an organism is often designated based on geographic range, population size, or declines in either. However, invertebrates, which comprise the bulk of animal diversity, are conspicuously absent from global frameworks that assess ...
Robert M. Goodsell, Ayco J. M. Tack, Fredrik Ronquist, Laura J. A. van Dijk, Elzbieta Iwaszkiewicz‐Eggebrecht, Andreia Miraldo, Tomas Roslin, Jarno Vanhatalo   +7 more
wiley   +1 more source

Commonalities of platelet dysfunction in heart failure with preserved ejection fraction and underlying comorbidities

ESC Heart Failure, Volume 12, Issue 2, Page 1013-1028, April 2025.
Abstract Heart failure with preserved ejection fraction (HFpEF) is characterized by a lack of a specific targeted treatment and a complex, partially unexplored pathophysiology. Common comorbidities associated with HFpEF are hypertension, atrial fibrillation, obesity and diabetes.
Giorgia D'Italia, Blanche Schroen, Judith M.E.M. Cosemans   +2 more
wiley   +1 more source