Results 191 to 200 of about 205,750 (245)

Somatic cell reprogramming for Parkinson's disease treatment

open access: yesIbrain, Volume 11, Issue 1, Page 59-73, Spring 2025.
The fundamental purpose of cell reprogramming to treat Parkinson's disease is to generate dopaminergic neurons (DAN) and do transplantation. There are two ways to accomplish this. One method is to induce cells into induced DA neurons (iDAN) directly or to induce cells into induced pluripotent stem cells and ultimately into iDAN in vitro. Another option
Xiaozhuo Li, Kevin Fang, Fengping Wang
wiley   +1 more source

Cordycepin mediates neuroprotection against apoptosis via ERK/CREB signaling activation in Aβ1–42‐induced neuronal cell models

open access: yesIbrain, Volume 11, Issue 1, Page 84-97, Spring 2025.
This study demonstrates cordycepin's neuroprotective effects against Aβ1–42‐induced apoptosis in neuronal cells, mediated through the activation of the extracellular signal‐regulated kinase/cyclic AMP‐responsive element‐binding protein (ERK/CREB) signaling pathway.
Wenshu Zhou   +6 more
wiley   +1 more source

Respiratory Syncytial Virus Under the Lens of Structure: From Prefusion Stabilization to Next‐Generation Immunotherapies

open access: yesiNew Medicine, EarlyView.
This illustration integrates key concepts covered in the review, including high‐risk populations, viral structure, host entry factors, the replication cycle, and licensed antibody‐based prevention strategies. ABSTRACT Respiratory syncytial virus (RSV) is a negative‐sense RNA virus belonging to the genus Orthopneumovirus within the family Pneumoviridae.
Zekai Cheng   +3 more
wiley   +1 more source

Two Problems for the Political Inclusion of Animals

open access: yesJournal of Applied Philosophy, EarlyView.
ABSTRACT In recent years, the field of animal ethics has taken a political turn, with scholars arguing that sentient nonhuman animals should be included in the political sphere. This article explores two key challenges arising from this turn towards the political inclusion of animals: the Conflict Problem and the Numbers Problem.
David Paaske, Angela K. Martin
wiley   +1 more source

Improper Primate Release Fuels Interspecific Mating: Cases of Two Mixed-Species Groups in Bangladesh. [PDF]

open access: yesEcol Evol
Ahmed T   +12 more
europepmc   +1 more source

Correction: Relaxation of selective constraint on the sweet-taste receptor gene TAS1R2 in lorisiform primates. [PDF]

open access: yesSci Rep
Ji Q   +9 more
europepmc   +1 more source

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