Results 191 to 200 of about 209,233 (218)

Preserved Spermatogenesis and Hormonal Function in Men Receiving a Pretomanid Regimen (BPaMZ) for Pulmonary Drug‐Resistant Tuberculosis

Clinical Pharmacology &Therapeutics, EarlyView.
Pretomanid is a component of the World Health Organization‐recommended treatment regimen for drug‐resistant tuberculosis in patients aged ≥ 14 years. While preclinical rodent studies identified testicular toxicity as a potential clinical liability at elevated doses, no corresponding effects were observed in nonhuman primates nor clinical hormone ...
Pauline Howell, Antonio Lombardi, William Brumskine, Lali Mikiashvili, Kim Boekelheide, Joanna Moreira, Alda Holsta, Matthew Betteridge, Lindsay Thompson, Angela Crook, Paul Bruinenberg, Maria Beumont, Eugene Sun, Francesca Conradie   +13 more
wiley   +1 more source

Yellow Fever Virus Surveillance in Callithrix spp. Marmosets during Epizootic Outbreak, Brazil, 2024-2025. [PDF]

Emerg Infect Dis
Siconelli MJL, de Almeida Dias JC, Machado EF, Cunha MS, de Azevedo Fernandes NCC, Guerra JM, Bonon L, Salomão AB, Werther K, Bürger KP, Carvalho AAB, Marques D, Lopes da Fonseca BA.   +12 more
europepmc   +1 more source

Relationship between home range and population density in mammals: the role of sociality, territoriality and habitat dimensionality

Ecography, EarlyView.
Organisms' energy requirements increase with body mass, leading to larger home range areas and lower population density. Previous research has highlighted the differential scaling of these variables in mammals, where species with large home ranges have higher density than expected due to increased home range overlap. Here we investigate this phenomenon
Luca Santini, Gianni Jacucci, Marlee A. Tucker   +2 more
wiley   +1 more source

Anatomical Evidence for a Uniquely Human Depressor Anguli Oris and a Novel Helplessness Signaling Hypothesis. [PDF]

Ann N Y Acad Sci
Rotenstreich L, Vituri A, Shahar M, Eliyahu K, Farkas O, Edery N, Moss L, Marom A.   +7 more
europepmc   +1 more source

Commonalities of platelet dysfunction in heart failure with preserved ejection fraction and underlying comorbidities

ESC Heart Failure, Volume 12, Issue 2, Page 1013-1028, April 2025.
Abstract Heart failure with preserved ejection fraction (HFpEF) is characterized by a lack of a specific targeted treatment and a complex, partially unexplored pathophysiology. Common comorbidities associated with HFpEF are hypertension, atrial fibrillation, obesity and diabetes.
Giorgia D'Italia, Blanche Schroen, Judith M.E.M. Cosemans   +2 more
wiley   +1 more source

Pediatric sensorimotor cortical responsiveness to intracerebral stimulation during stereoelectroencephalographic monitoring: Age effects and area specificity

Epilepsia, EarlyView.
Abstract Objective This study was undertaken to determine how age influences clinical responsiveness to intracerebral electrical stimulation (IES) in children across primary and secondary sensorimotor cortices and to assess age effects on response complexity and area‐specific responsiveness.
Giulia Nobile, Laura Tassi, Marta Ponzano, Piergiorgio d'Orio, Alessandro Consales, Luca Bosisio, Stefano Francione, Gabriele Arnulfo, Maria Pia Sormani, Lino Nobili, Roberto Mai   +10 more
wiley   +1 more source

WONOEP XVII appraisal: The role of the extracellular matrix in epilepsy

Epilepsia, EarlyView.
Abstract The extracellular matrix (ECM) is composed of proteoglycans and glycoproteins that regulate the external environment surrounding neurons, glia, and the vascular system. The ECM is vital for maintaining the structure and function of the brain and also acts as a reservoir for various signaling molecules and neurotransmitters, modulating synaptic
Eleonora Lugara, Erwin A. van Vliet, Alessia Romagnolo, Kevin Staley, Kyle P. Lillis, Chris Dulla, David C. Henshall, Katja Kobow   +7 more
wiley   +1 more source

Brain–Computer Interfaces: The Dawn of a New Era in Disease Treatment

Exploration, EarlyView.
This study investigates the potential of brain–computer interface (BCI) technology in treating neuropsychiatric disorders, such as movement and communication barriers. Our review examines the history, signal paradigms, and diverse applications of BCI while also discussing ongoing research into novel materials and emerging technologies that offer ...
Yuqi Feng, Wangzheqi Zhang, Jun Chen, Huang Wu, Lei Wu, Yanhao Qiu, Xiaoming Deng, Chenglong Zhu, Yisheng Chen, Zhijie Zhao, Changli Wang, Xiaomin Zhang   +11 more
wiley   +1 more source

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Non-human primates as a model for human development

Stem Cell Reports, 2021
Tomonori Nakamura, Mitinori Saitou, Tomoyuki Tsukiyama   +2 more
exaly