Results 261 to 270 of about 492,641 (339)

Nanostructured drug delivery systems for posterior segment eye diseases: Strategies to defy ocular barriers

open access: yesBMEMat, EarlyView.
Efficient drug delivery to the posterior segment of the eye has long been a challenging issue due to the complex ocular barriers. The review focuses on the promise held by nanoplatforms for barrier penetration and the key mechanisms involved, also highlighting their advantages in achieving efficient drug delivery and superior treatment of PSEDs ...
Yifan Shen   +7 more
wiley   +1 more source

Remodeling of <i>XIST</i> regulatory landscape during primate evolution. [PDF]

open access: yesSci Adv
Cazottes E   +12 more
europepmc   +1 more source

New opportunities for bioscaffold‐enabled spinal cord injury repair

open access: yesBMEMat, EarlyView.
Schematic illustration of bioscaffolds for spinal cord injury repair. We summarize the effects of bioscaffold properties on SCI repair, highlight different types of bioscaffolds, various fabrication strategies, and in vivo transformations for the clinical development of SCI‐repairing bioscaffolds.
Xiaoqing Qi   +11 more
wiley   +1 more source

Nanomaterials‐mediated glycolysis rewriting to potentiate tumor immunotherapy

open access: yesBMEMat, EarlyView.
This review systematically summarizes cutting‐edge advances in glycolysis‐rewiring nanomedicines, emphasizing their mechanisms in reversing immunosuppression and reinvigorating antitumor immune responses. Challenges in clinical translation and future directions for designing multifunctional metabolic‐immune modulators are also critically discussed ...
Zilin Ma   +9 more
wiley   +1 more source

Inferences about fossil hominin locomotion through 3D morphometric analysis of wrist ligament insertion sites. [PDF]

open access: yesSci Rep
Casado A   +9 more
europepmc   +1 more source

The flexible, the stereotyped and the in‐between: putting together the combinatory tool use origins hypothesis

open access: yesBiological Reviews, EarlyView.
ABSTRACT Tool use research has long made the distinction between tool using that is considered learned and flexible, and that which appears to be instinctive and stereotyped. However, animals with an inherited tool use specialisation can exhibit flexibility, while tool use that is spontaneously innovated can be limited in its expression and facilitated
Jennifer A. D. Colbourne   +1 more
wiley   +1 more source

Video-Sound Recording Devices Reveal Multiple Drivers of Nocturnal Vocalizations in Tibetan Macaques. [PDF]

open access: yesEcol Evol
Gao X   +10 more
europepmc   +1 more source

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