Results 151 to 160 of about 5,990,152 (267)

Brain defence by the extracellular matrix protein Cochlin. [PDF]

Commun Biol
Ghosh R, Jeong I, Rajamannar P, Jurisch-Yaksi N, Lee BTK, Jesuthasan S.   +5 more
europepmc   +1 more source

Integrated PANoptosis Profiling Identifies Immunosuppressive Subtypes and a Prognostic Signature With Functional Validation of MLKL in Glioblastoma

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective The prognosis of glioblastoma (GBM) remains highly unfavorable, largely due to high tumor heterogeneity and an immunosuppressive microenvironment. However, the functional role of PANoptosis in this context is poorly understood. Methods Patients were stratified via K‐means clustering. A risk score model was constructed using prognosis‐
Langfei Tian, Minghui Zhao, Yuanbo Hu, Kaiyue Wang, Haiguang Liu, Zetong Bai, Kebin Zheng   +6 more
wiley   +1 more source

RiTeK: A Dataset for Large Language Models Complex Reasoning over Textual Knowledge Graphs in Medicine. [PDF]

Find ACL ACL
Huang J, Li M, Yao Z, Li D, Zhang Y, Yang Z, Xiao Y, Ouyang F, Li X, Han S, Yu H.   +10 more
europepmc   +1 more source

Validation of a Cellular Imaging‐Based Method as a Potential Biomarker for SPG4 Hereditary Spastic Paraplegia

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Hereditary Spastic Paraplegia (HSP) comprises a group of rare genetic diseases characterized by length‐dependent axonal degeneration of the corticospinal tracts and dorsal columns, whose main clinical feature is spastic gait. Pathogenic variants in the SPG4 gene cause Spastic Paraplegia Type 4 (SPG4‐HSP), the most common form of HSP.
Gaia Fattorini, Valerio Licursi, Gianmarco Dalla Zanna, Flavio Dal Canto, Melissa Barghigiani, Nunzio Setola, Salvatore Rossi, Antonio Funcis, Filippo M. Santorelli, Gabriella Silvestri, Carlo Casali, Francesca Sardina, Cinzia Rinaldo   +12 more
wiley   +1 more source

Fully Characterizing Lossy Catalytic Computation. [PDF]

Algorithmica
Folkertsma M, Mertz I, Speelman F, Tupker Q.   +3 more
europepmc   +1 more source

Intracerebral Hemorrhage Induces Monocyte TNF Signaling in Patients That Is Suppressed by BAF312

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Intracerebral hemorrhage (ICH) causes high morbidity and mortality, with neurotoxic inflammation driven by infiltrating monocytes. This study is an in‐depth longitudinal examination of the immune response during the first week of ICH in the presence and absence of the immunomodulatory drug BAF312 (Siponimod).
Jonathan Howard DeLong, Sebastian Díaz‐Pérez, Kevin Navin Sheth, Jang‐Ho Cha, C. J. Malanga, Patricia G. M. Wagner, Nicole Pezous, Aurelie Hanin, Kyle B. Walsh, H. E. Hinson, Lauren Hachmann Sansing   +10 more
wiley   +1 more source

Development of mitochondrial mutator pigs exhibiting increased mitochondrial DNA mutations and premature aging via prime editing. [PDF]

Sci Adv
Chen F, Liang Y, Zheng W, Yao A, Wang N, Chen H, Zhuang Z, Lian M, Zhao Y, Ouyang Z, Zhou Z, Ge W, Liu Q, Ye Y, Lai L, Wang K.   +15 more
europepmc   +1 more source

White Matter and Perivascular Imaging Changes in Alzheimer's Disease and Cerebral Amyloid Angiopathy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Peak‐width of skeletonized mean diffusivity (PSMD) and diffusion tensor imaging–analysis along the perivascular space (DTI‐ALPS), reflecting white matter integrity and glymphatic function, are altered in Alzheimer's disease (AD).
Debina Laishram, Guangwei Du, Sangam Kanekar, Nandakumar Nagaraja   +3 more
wiley   +1 more source

VO FUNCTION

The theory proposes constructing a class of arithmetic functions that is "aesthetic" and "structured," denoted by \mathbf{V}, aiming to unify classical functions such as the identity function (\mathbit{id}), Euler's totient function (\mathbit{\varphi ...
Vô, Pseudonym
core  

Persistent Epithelial Defect After Bullae Rupture With Netarsudil. [PDF]

Cureus
Mansoori T.
europepmc   +1 more source