Results 131 to 140 of about 823,935 (279)
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
Molecular Oncology, EarlyView.We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu +10 more
wiley +1 more source
PERMUTATION GROUPS WITH BOUNDED MOVEMENT ATTAINING THE BOUNDS FOR ODD PRIMES [PDF]
Journal of Sciences, Islamic Republic of Iran, 1998 Let G be a transitive permutation group on a set ? and let m be a positive integer. If no element of G moves any subset of ? by more than m points, then |? | [2mp I (p-1)] wherep is the least odd primedividing |G |. When the bound is attained, we show
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Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
Dedekind domains: Overrings and semi-prime elements [PDF]
Pacific Journal of Mathematics, 1965 openaire +2 more sources
NKCC1: A key regulator of glioblastoma progression
Molecular Oncology, EarlyView.Glioblastoma (GBM) progression is driven by disrupted chloride cotransporter homeostasis. NKCC1 is highly expressed in stem‐like, astrocytic, and progenitor cells, correlating with earlier recurrence, while overall survival remains unaffected. NKCC1 serves as a prognostic marker and potential therapeutic target, linking chloride transporter imbalance ...
Anja Thomsen +5 more
wiley +1 more source
On generalization of prime, weakly prime and almost prime elements in multiplicative lattices
International Journal of Algebra, 2014 Sachin Ballal, Vilas Kharat
openaire +1 more source
Forbidden Subgraphs of Prime Order Element Graph
In this paper, we study different forbidden subgraph characterizations of the prime-order element graph $Γ(G)$ defined on a finite group $G$. Its set of vertices is the group $G$ and two vertices $x,y \in G$ are adjacent if the order of $xy$ is prime. More specifically, we investigate the conditions when $Γ(G)$ is perfect, cograph, chordal, claw-free ...
Manna, Tapa +2 more
openaire +2 more sources
Molecular Oncology, EarlyView.CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak +10 more
wiley +1 more source
Endomorphism algebras of abelian varieties with large cyclic 2-torsion field over a given field. [PDF]
Res Number TheoryGoodman P.
europepmc +1 more source