Results 31 to 40 of about 216,097 (247)

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

open access: yesFEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi   +5 more
wiley   +1 more source

Quasirecognition by prime graph of U_3(q) where 2 < q =p^{alpha} < 100 [PDF]

open access: yesInternational Journal of Group Theory, 2012
Let G be a finite group and let Gamma(G) be the prime graphof G. Assume 2 < q = p^{alpha} < 100 . We determine finite groupsG such that Gamma(G) = Gamma(U_3(q)) and prove that if q neq3, 5, 9, 17, then U_3(q) is quasirecognizable by prime graph,i.e., if ...
Ali Iranmanesh   +3 more
doaj  

Preliminary validation of the PRImary care facility Management Evaluation tool (PRIME-Tool), a national facility management survey implemented in Ghana

open access: yesBMC Health Services Research, 2019
Background The management quality of healthcare facilities has consistently been linked to facility performance, but available tools to measure management are costly to implement, often hospital-specific, not designed for low- and middle-income countries
Jhanna Uy   +9 more
doaj   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

open access: yesFEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo   +2 more
wiley   +1 more source

On a thin set of integers involving the largest prime factor function

open access: yesInternational Journal of Mathematics and Mathematical Sciences, 2003
For each integer n≥2, let P(n) denote its largest prime factor. Let S:={n≥2:n does not divide P(n)!} and S(x):=#{n≤x:n∈S}. Erdős (1991) conjectured that S is a set of zero density.
Jean-Marie De Koninck, Nicolas Doyon
doaj   +1 more source

The role and implications of mammalian cellular circadian entrainment

open access: yesFEBS Letters, EarlyView.
At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
wiley   +1 more source

4′-Methoxyresveratrol Alleviated AGE-Induced Inflammation via RAGE-Mediated NF-κB and NLRP3 Inflammasome Pathway

open access: yesMolecules, 2018
Advanced glycation end products (AGEs) could interact with the receptor for AGE (RAGE) as a sterile danger signal to induce inflammation. 4′-methoxyresveratrol (4′MR), a polyphenol derived from Dipterocarpaceae, has not been studied for its ...
Wenzhe Yu   +4 more
doaj   +1 more source

Primes and Factors [PDF]

open access: yesNature, 1938
DR. GEORGE KAVAN was born at Prague in 1877. His parents were Francis Kavan, a musical conductor and a composer of merit, and his wife Miroslava, an ardent supporter of the civil rights of women. After studying mathematics, physics and astronomy, Kavan became in 1900 chief assistant at the Astronomical Institute of the Czech University at Prague, where
openaire   +1 more source

Molecular bases of circadian magnesium rhythms across eukaryotes

open access: yesFEBS Letters, EarlyView.
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley   +1 more source

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