Results 121 to 130 of about 2,976 (243)

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

open access: yesMolecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu   +13 more
wiley   +1 more source

Symmetric Bipartite Graphs of Prime Valency

open access: yesEuropean Journal of Combinatorics, 1990
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
openaire   +1 more source

Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma

open access: yesMolecular Oncology, EarlyView.
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski   +10 more
wiley   +1 more source

Cubic semisymmetric graphs of order $ 40p $ [PDF]

open access: yesریاضی و جامعه
A simple graph $\Gamma$ is called semisymmetric if it is regular and edge-transitive but not vertex-transitive. A simple graph $\Gamma$ is called cubic whenever it is $ 3 $-regular.
Mohammad Reza Salarian   +1 more
doaj   +1 more source

Substitution-closed pattern classes

open access: yes, 2011
The substitution closure of a pattern class is the class of all permutations obtained by repeated substitution. The principal pattern classes (those defined by a single restriction) whose substitution closure can be defined by a finite number of ...
Atkinson, M.D.   +7 more
core   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

open access: yesMolecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim   +3 more
wiley   +1 more source

The graph of the square mapping on the prime fields

open access: yes, 1996
The action of the quadratic map f (x) = x2 on the multiplicative groups Fp∗ of the prime fields is examined in terms of an associated directed graph that sends an edge from each element to its image.
Rogers, Thomas D., Thomas D. Rogers
core   +1 more source

Almost-Ramanujan graphs and prime gaps

open access: yesEuropean Journal of Combinatorics, 2015
The method of Murty and Cioabă shows how one can use results about gaps between primes to construct families of almost-Ramanujan graphs. In this paper we give a simpler construction which avoids the search for perfect matchings and thus eliminates the need for computation.
openaire   +4 more sources

Prime Cordial Graphs

open access: yes, 2017
Let be a graph. A prime cordial labeling of with vertex set is a bijection from to such that if each edge is assigned the label when gcd and otherwise, then the difference between the number of edges labeled with and the number of edges labeled with is at most . A graph which admits prime cordial labeling is called a prime cordial graph. In
M. Bhuvaneshwari   +2 more
openaire   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

open access: yesMolecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller   +10 more
wiley   +1 more source

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