Results 151 to 160 of about 2,976 (243)

Innate Immune Reprogramming Mediated by Endogenous Retroelement Dysregulation Drives Multiple Sclerosis Progression

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
Epigenetic reprogramming in hematopoietic stem and progenitor cells (HSPCs) and downstream myeloid cells, mediated by H3.3 downregulation and endogenous retroelement (ERE) overexpression, contributes to the progression of multiple sclerosis (MS). ABSTRACT Background Skewed myelopoiesis in the bone marrow has been identified as a key driver of multiple ...
Li‐Mei Xiao   +6 more
wiley   +1 more source

On the prime graph question for integral group rings of 4-primary groups I

open access: yes, 2017
We study the Prime Graph Question for integral group rings. This question can be reduced to almost simple groups by a result of Kimmerle and Konovalov. We prove that the Prime Graph Question has an affirmative answer for all almost simple groups having a
Leo Margolis, Andreas Bächle
core   +1 more source

ALDOA Promotes Glycolysis and NLRP3/GSDMD Pyroptosis to Accelerate ALS Progression

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is characterized by progressive motor neuron degeneration. Glycolytic dysregulation is implicated in disease progression, yet the underlying mechanisms remain unclear. This study investigates how Aldolase A (ALDOA) drives ALS progression through glycolysis‐mediated motor neuron pyroptosis.
Kaixin Yan   +9 more
wiley   +1 more source

Relationship Between Neurologic Symptoms and Signs and FMR1 Genotype in Premutation Carriers

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background and Objectives Fragile X‐associated Tremor/Ataxia Syndrome (FXTAS) is the most severe late‐onset condition caused by a premutation in the FMR1 gene, characterized by expanded CGG triplet repeats of 55–200. Clinical presentations of FXTAS, including gait ataxia, kinetic tremor, cognitive decline, and rare Parkinsonism, are linked to ...
Flora Tassone   +8 more
wiley   +1 more source

THE TRIPLE IDEMPOTENT GRAPH OF THE RING Z_n

open access: yesBarekeng
Let  be a commutative ring, and  denote the set of all idempotent elements of . The triple idempotent graph of , denoted by , is defined as an undirected simple graph whose vertex set .
Vika Yugi Kurniawan   +2 more
doaj   +1 more source

Primitive graph algebras

open access: yes, 2014
Let $E = (E^0, E^1, s,r)$ be an arbitrary directed graph (i.e., no restriction is placed on the cardinality of $E^0$, or of $E^1$, or of $s^{-1}(v)$ for $v\in E^0$).
Abrams, Gene
core  

A Theorem on the Prime Graph of 2x2 - Matrix Ring of Z2

open access: yes, 2016
In this paper we consider prime graph of R (denoted by ) of an associative ring R (introduced bySatyanarayana, Syam Prasad and Nagaraju [5]).This short paper is divided into two sections. Section-1 is devoted for preliminary definitions.
, Satyanarayana Bhavanari, Srinivasulu Dev
core   +1 more source

Ofatumumab in Myelin Oligodendrocyte Glycoprotein Antibody–Associated Disease: A Comparison With Rituximab

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To evaluate the efficacy and safety of ofatumumab in patients with myelin oligodendrocyte glycoprotein antibody–associated disease (MOGAD), and compare it with rituximab. Methods We conducted a single–center, observational study including 22 MOGAD patients treated with ofatumumab and 21 treated with rituximab.
Yuxin Fan   +5 more
wiley   +1 more source

A novel approach to explore common prime divisor graphs and their degree based topological descriptor.

open access: yesPLoS ONE
For the construction of a common prime divisor graph, we consider an integer [Formula: see text] with its prime factorization, where [Formula: see text] are distinct primes and [Formula: see text] are fixed positive integers. Every divisor of the integer
Ali N A Koam   +3 more
doaj   +1 more source

On the Graph Isomorphism Completeness of Directed and Multidirected Graphs

open access: yesMathematics
The category of directed graphs is isomorphic to a particular category whose objects are labeled undirected bipartite graphs and whose morphisms are undirected graph morphisms that respect the labeling. Based on this isomorphism, we begin by showing that
Sebastian Pardo-Guerra   +2 more
doaj   +1 more source

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