Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To investigate which baseline clinical and imaging characteristics best predict TSPO‐PET‐measurable reduction in glial activation following treatment of multiple sclerosis (MS), to utilize this information for designing more efficient biomarker‐based clinical trials targeting glial activation.
Marlene T. Morch +5 more
wiley +1 more source
The pan-African natural products library compounds oleanolic acid, poinsettifolin B, and rhuschalcone III disrupt SARS-CoV-2 spike-host ACE2 interactions and SARS-CoV-2 replication. [PDF]
BMC Pharmacol ToxicolTjegbe MJM +10 more
europepmc +1 more source
NONUNITAL PRIME RINGS GRADED BY ORDERED GROUPS
Let G be a group with identity element e , and suppose that S is an associative G -graded ring
JOHAN ÖINERT +11 more
core +1 more source
Deep Learning Pose Estimation for Phenotyping of Co‐Occurring Hyperkinetic Movement Disorders
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To explore whether routine outpatient video combined with deep learning‐based pose estimation and clinically interpretable kinematic features can support multi‐label phenotyping of co‐occurring hyperkinetic movement disorders (HMDs).
Laura Cif +17 more
wiley +1 more source
Self-assembly Monte Carlo reveals localized entanglement in giant polymer melts. [PDF]
Nat CommunFornasa E, Slongo F, Micheletti C.
europepmc +1 more source
Gravity‐Dependent Modulation of Downbeat Nystagmus: Insights From Velocity‐Storage Dysfunction
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Downbeat nystagmus varies with head position, a phenomenon termed gravity‐dependent modulation. We aimed to clarify its mechanism using a velocity‐storage model. Methods In 10 patients with downbeat nystagmus due to cerebellar disorders, we recorded eye movements at different pitch‐ and roll‐axis head positions.
Ji‐Hyung Park +5 more
wiley +1 more source
The complete chloroplast genome of <i>Cynanchum hemsleyanum</i> and its phylogenetic analysis. [PDF]
Mitochondrial DNA B ResourLi M, Xu Y, Xu R, Bi K, Xiong C.
europepmc +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Background Hereditary Spastic Paraplegia (HSP) comprises a group of rare genetic diseases characterized by length‐dependent axonal degeneration of the corticospinal tracts and dorsal columns, whose main clinical feature is spastic gait. Pathogenic variants in the SPG4 gene cause Spastic Paraplegia Type 4 (SPG4‐HSP), the most common form of HSP.
Gaia Fattorini +12 more
wiley +1 more source
Genetic testing and exchangeable copper can improve the accuracy of Wilson disease diagnoses. [PDF]
Hepatol CommunBerenguer M +15 more
europepmc +1 more source
Rings with involution and the prime radical [PDF]
Pacific Journal of Mathematics, 1977 Baxter, W. E., Casciotti, L. A.
openaire +3 more sources