Results 41 to 50 of about 15,791 (312)

Emapalumab for Immune Effector Cell‐Associated Hemophagocytic Lymphohistiocytosis‐Like Syndrome Following CD19‐Directed CAR‐T in Two Patients With B‐ALL: Clinical and Biomarker Correlates

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Immune effector cell‐associated hemophagocytic lymphohistiocytosis‐like syndrome (IEC‐HS) is a life‐threatening hyperinflammatory toxicity distinct from cytokine release syndrome (CRS) and neurotoxicity following chimeric antigen receptor T‐cell (CAR‐T) therapy. In a single‐institution retrospective cohort of pediatric and young adult patients
Thomas J. Galletta   +6 more
wiley   +1 more source

A Bibliometric Analysis of Publications in Uremic Toxins From 1991 to 2024

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Uremic toxins are a growing area of research in nephrology, with significant implications in the progression and treatment of chronic kidney disease (CKD) and the management of end‐stage kidney disease (ESKD). This bibliometric analysis aims to evaluate the global research trends, key contributors, and the impact of publications in ...
Yuh‐Shan Ho   +7 more
wiley   +1 more source

On (?,?)-Derivations and Commutativity of Prime and Semi prime ?-rings

open access: yesمجلة بغداد للعلوم, 2016
Let R be a ?-ring, and ?, ? be two automorphisms of R. An additive mapping d from a ?-ring R into itself is called a (?,?)-derivation on R if d(a?b) = d(a)? ?(b) + ?(a)?d(b), holds for all a,b ?R and ???. d is called strong commutativity preserving (SCP)
Baghdad Science Journal
doaj   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Ideals on the Quantum Plane’s Jet Space

open access: yesMathematics, 2020
The goal of this paper is to introduce some rings that play the role of the jet spaces of the quantum plane and unlike the quantum plane itself possess interesting nontrivial prime ideals.
Andrey Glubokov
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

On derivations of prime and semi-prime Gamma rings

open access: yesBoletim da Sociedade Paranaense de Matemática, 2017
The concept of $\Gamma$-ring is a generalization of ring. Twoimportant classes of $\Gamma$-rings are prime and semi-prime$\Gamma$-rings. In this paper, we consider the concept of derivations on prime and semi-prime $\Gamma$-rings and we study some of their properties.
Leili Kamali Ardakani   +2 more
openaire   +4 more sources

Constacyclic codes over finite local Frobenius non-chain rings of length 5 and nilpotency index 4

open access: yesAnalele Stiintifice ale Universitatii Ovidius Constanta: Seria Matematica, 2020
The family of finite local Frobenius non-chain rings of length 5 and nilpotency index 4 is determined, as a by-product all finite local Frobenius non-chain rings with p5 elements (p a prime) and nilpotency index 4 are given.
Castillo-Guillén C. A.   +1 more
doaj   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

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