Results 211 to 220 of about 640,811 (318)

Programmable NIR Responsive Nanocomposite Enables Noninvasive Intratympanic Delivery of Dexamethasone to Reverse Cisplatin Induced Hearing Loss

open access: yesAdvanced Science, EarlyView.
In this study, saponin‐coated silica@gold nanocarriers responsive to NIR radiation is developed to enhance intratympanic drug delivery for cisplatin‐induced hearing loss (CIHL) treatment. The biocompatibility and oto‐protective properties are validated both in vitro and in vivo.
Rawand A. Mustafa   +6 more
wiley   +1 more source

Intranasal prime-boost RNA vaccination elicits potent T cell response for lung cancer therapy. [PDF]

open access: yesSignal Transduct Target Ther
Li H   +6 more
europepmc   +1 more source

Ultralow‐Dimensionality Reduction for Identifying Critical Transitions by Spatial‐Temporal PCA

open access: yesAdvanced Science, EarlyView.
The proposed spatial‐temporal principal component analysis (stPCA) method analytically reduces high‐dimensional time‐series data to a single latent variable by transforming spatial information into temporal dynamics. By preserving the temporal properties of the original data, stPCA effectively identifies critical transitions and tipping points.
Pei Chen   +6 more
wiley   +1 more source

A Multifunctional Nanodelivery System Modified by Fusion Peptides Acts as Teriparatide Carrier for Noise‐Induced Hearing Loss Therapy

open access: yesAdvanced Science, EarlyView.
The fusion peptide LR27‐modified thermosensitive nanodelivery system exhibits both hair cell targeting and inner ear penetrating properties. This system sustainably and effectively delivers PTH1‐34 to the inner ear of a hearing loss mouse model via the synergistic effects of multiple peptides, achieving satisfactory hearing protection through ...
Jiawen Li   +12 more
wiley   +1 more source

Advancements in Biochar as a Sustainable Adsorbent for Water Pollution Mitigation

open access: yesAdvanced Science, EarlyView.
Biochar, obtained through pyrolysis of organic waste, serves as a sustainable solution for wastewater treatment due to its adaptability and low‐cost nature. This review comprehensively examines recent advancements in biochar production, functional modifications, and applications, highlighting the integration of machine learning and artificial ...
Devika Laishram   +3 more
wiley   +1 more source

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