Results 221 to 230 of about 640,811 (318)

Co-Delivery of Dacarbazine and miRNA 34a Combinations to Synergistically Improve Malignant Melanoma Treatments. [PDF]

Drug Des Devel Ther
Ding B, Li M, Zhang J, Zhang X, Gao H, Gao J, Shen C, Zhou Y, Li F, Liu A.   +9 more
europepmc   +1 more source

From De Novo Conceived Small Molecules to Multifunctional Supramolecular Nanoparticles: Dual Biofilm and T3SS Intervention, Enhanced Foliar Affinity, and Effective Rice Disease Control

Advanced Science, EarlyView.
From de novo engineered bioactive molecules BtP27 to the multifunctional supramolecular material BtP27@β‐CD with a sunflower‐shaped morphology: its pragmatic applications in augmenting foliar affinity, disrupting biofilms and T3SS, and managing rice pathologies. Abstract Conventional antimicrobials typically exhibit suboptimal deposition on rice leaves,
Xianfu Mu, Kongjun Liu, Jinghan Yang, Juan Liu, Fengpei Du, Gefei Hao, Peiyi Wang   +6 more
wiley   +1 more source

Novel nanoemulsion adjuvant stabilized by TPGS possesses equivalent physicochemical properties, Turbiscan stability, and adjuvanticity to AS03 for eliciting robust immunogenicity of subunit vaccines in mice. [PDF]

Hum Vaccin Immunother
Yin Q, Song S, Liu Z.
europepmc   +1 more source

Advances in Electrical Materials for Bone and Cartilage Regeneration: Developments, Challenges, and Perspectives

Advanced Science, EarlyView.
This review explores the challenges of treating bone and cartilage defects, emphasizing the role of endogenous electric fields in bone and cartilage regeneration. It highlights recent advancements in electroactive biomaterials, including nanogenerators, piezoelectric materials, triboelectric scaffold, and zwitterionic hydrogels.
Yubin Yao, Xi Cui, Shenglong Ding, Ketao Wang, Mingzhu Zhang   +4 more
wiley   +1 more source

Characterization and immunogenicity assessment of MERS-CoV pre-fusion spike trimeric oligomers as vaccine immunogen. [PDF]

Hum Vaccin Immunother
Ahuja R, Vishwakarma P, Raj S, Kumar V, Khatri R, Lohiya B, Saxena S, Kaur G, Singh G, Asthana S, Ahmed S, Samal S.   +11 more
europepmc   +1 more source

Paclitaxel/Luteolin Coloaded Dual‐Functional Liposomes for Esophageal Cancer Therapy

Advanced Science, EarlyView.
The authors develop a pH‐sensitive aptamer‐modified liposome (EA2‐PSL‐PTX/LUT) to illustrate a strategy for the precise delivery of combinational chemotherapeutic drugs for esophageal squamous cell carcinoma (ESCC) targeted therapy. EA2‐PSL‐PTX/LUT provides efficient co‐loading, tumor targeting, and controlled release of luteolin and paclitaxel ...
Congyong Sun, Fei Xie, Huiyun Zhang, Lulu Feng, Yuting Wang, Chaofan Huang, Zhizhen Cui, Chao Luo, Li Zhang, Qilong Wang   +9 more
wiley   +1 more source

Multilayer Adjuvanted Influenza Protein Nanoparticles Improve Intranasal Delivery and Antigen-Specific Immunity. [PDF]

ACS Nano
Park J, Pho T, Bhatnagar N, Mai LD, Rodriguez-Otero MR, Pal SS, Le CTT, Jenison SE, Li C, May GA, Arioka M, Kang SM, Champion JA.   +12 more
europepmc   +1 more source

Resilient Membranized Coacervates Formed through Spontaneous Wrapping of Heat‐Destabilized Lipid Bilayers around Coacervate Droplets

Advanced Science, EarlyView.
We present a universal way to wrap liposomes around coacervate droplets. Membrane‐enclosed coacervates form when heat‐destabilized liposomes are mixed with coacervates. Membranized coacervates (MCs) can survive pH and ionic strength fluctuations, osmotic stress, and low temperatures.
Sadaf Javed, Evan Spruijt
wiley   +1 more source

Combination of DMDD with Nanoparticles Effective Against Diabetic Kidney Disease in vitro. [PDF]

Int J Nanomedicine
Huang XM, Guo YX, Pang QL, Yan XY, Yan H, Li JY, Tang GL, Jiang HX, Zhang HL.   +8 more
europepmc   +1 more source

ROS‐Activated Nanohydrogel Scaffolds with Multi‐Factors Controlled Release for Targeted Dual‐Lineage Repair of Osteochondral Defects

Advanced Science, EarlyView.
ROS‐activated nanohydrogels composite bilayer scaffolds are rationally designed for targted dual‐lineage repair of osteochondral defects. The as‐prepared nanohydrogel scaffolds provided 3D culture and induced dual‐lineage differentiation of BMSCs in vitro, efficiently inhibited early‐stage inflammation by rapidly releasing DS and improved cartilage and
Xiuhui Wang, Shunli Wu, Ruiyang Li, Huijian Yang, Yue Sun, Zijie Cao, Xiao Chen, Yan Hu, Hao Zhang, Zhen Geng, Long Bai, Zhongmin Shi, Ke Xu, Hongbo Tan, Jiacan Su   +14 more
wiley   +1 more source