Results 241 to 250 of about 640,811 (318)
Isoquercitrin Alleviates Diabetic Nephropathy by Inhibiting STAT3 Phosphorylation and Dimerization
This study identified a natural compound, isoquercitrin, which significantly alleviated kidney inflammation and fibrosis by inhibiting STAT3 activity. Isoquercitrin forms a strong, noncovalent bond that directly binds to STAT3. Isoquercitrin binds to the pY+1 pocket of the SH2 domain of STAT3 via hydrogen bonding with Ser668, Gln635, and Gln633 ...
Chen Xuan+12 more
wiley +1 more source
Infinite-Dimensional Quantum Entropy: The Unified Entropy Case. [PDF]
Gielerak R, Wiśniewska J, Sawerwain M.
europepmc +1 more source
The globular shape and hydrophobicity of zein made it unsuitable to be processed in pure aqueous environment. Pepsin‐mediated hydrolysis converts zein into water‐soluble and fibril‐forming peptides with a bioconversion rate exceeding 70%, enabling the self‐assembly of amyloid‐like nanofibrils.
Mingqin Li+8 more
wiley +1 more source
A comparison between adjuvant and delivering functions of iron oxide and calcium phosphate nanoparticles, using a model protein against Brucella melitensis. [PDF]
Goudarzi T+4 more
europepmc +1 more source
A multi‐functional shear‐thinning hydrogel is engineered to treat enterocutaneous fistulas. This hydrogel can resist external pressures allowing it to remain within the fistula tract and is shown to have significant antimicrobial, pro‐healing, and anti‐inflammatory properties, which were validated in in vitro and in vivo experiments.
Jinjoo Kim+6 more
wiley +1 more source
Management succinate release through SDHA by G protein-coupled receptor 91 signal, TRAP1, and SIRT3 regulation in lung cancer cells by NAR nanoparticles. [PDF]
Ragab EM+3 more
europepmc +1 more source
A multi‐functional photo‐enzymatic nanoreactor HRP@Fe‐NU‐1003 is developed through co‐immobilization of horseradish peroxidase and FeCl2 on a photosensitive metal–organic frameworks NU‐1003. This material showcases remarkable sensitivity and efficacy in both detecting and subsequently photo‐degrading chloramphenicol residues in food products.
Lu Ran+5 more
wiley +1 more source
Self-disassembling nanoparticles as oral nanotherapeutics targeting intestinal microenvironment. [PDF]
Park J+6 more
europepmc +1 more source
Occlusion of tumor blood vessels represents a promising yet challenging approach in cancer treatment. Herein, supramolecularly engineered platelets conjugated with morphology‐transformable nanoparticles is developed for precise tumor embolization. The engineered platelets actively accumulate at tumor sites following induced blood vessel injury.
Junyan Li+9 more
wiley +1 more source