Results 71 to 80 of about 626,535 (304)
Proceedings of the American Mathematical Society, 1991 Let P 1 , … , P n ( n ≥ 2 ) {P_1}, \ldots ,{P_n}\left ( {n \geq 2} \right ) be not necessarily distinct nonzero prime ideals in ...
Heitmann, Raymond C., McAdam, Stephen
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Disruption of the autoinhibited state primes the E3 ligase parkin for activation and catalysis
EMBO Journal, 2015 The PARK2 gene is mutated in 50% of autosomal recessive juvenile parkinsonism (ARJP) cases. It encodes parkin, an E3 ubiquitin ligase of the RBR family.
Atul Kumar +12 more
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FEBS Letters, EarlyView.Bifidobacterium bifidum establishes symbiosis with infants by metabolizing lacto‐N‐biose I (LNB) from human milk oligosaccharides (HMOs). The extracellular multidomain enzyme LnbB drives this process, releasing LNB via its catalytic glycoside hydrolase family 20 (GH20) lacto‐N‐biosidase domain.
Xinzhe Zhang +5 more
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The role and implications of mammalian cellular circadian entrainment
FEBS Letters, EarlyView.At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
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Experimental Mathematics, 1998 This paper examines the question of whether there is an unbounded walk of bounded step size along Gaussian primes. Percolation theory predicts that for a low enough density of random Gaussian integers no walk exists, which suggests that no such walk exists along prime numbers, since they have arbitrarily small density over large enough regions.
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Small gaps between primes [PDF]
Graduate Studies in Mathematics, 2013 We introduce a renement of the GPY sieve method for studying prime k-tuples and small gaps between primes. This renement avoids previous limitations of the method and allows us to show that for each k, the prime k-tuples conjecture holds for a positive ...
J. Maynard
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Molecular bases of circadian magnesium rhythms across eukaryotes
FEBS Letters, EarlyView.Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
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From gr8 to great: Lexical access to SMS shortcuts
Frontiers in Psychology, 2012 Many contemporary texts include shortcuts, such as cu or phones4u. The aim of this study was to investigate how the meanings of shortcuts are retrieved. A primed lexical decision paradigm was used with shortcuts and the corresponding words as primes. The
Lesya eGanushchak +2 more
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Consecutive primes in tuples [PDF]
, 2014 In a recent advance towards the Prime $k$-tuple Conjecture, Maynard and Tao have shown that if $k$ is sufficiently large in terms of $m$, then for an admissible $k$-tuple $\mathcal{H}(x) = \{gx + h_j\}_{j=1}^k$ of linear forms in $\mathbb{Z}[x]$, the set
Banks, William D. +2 more
core
Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10
FEBS Letters, EarlyView.Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang +8 more
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