Results 71 to 80 of about 71,662 (302)
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi +5 more
wiley +1 more source
Iwasawa theory for modular forms at supersingular primes [PDF]
Let f=\sum a_nq^n be a normalised eigen-newform of weight k\ge2 and p an odd prime which does not divide the level of f. We study a reformulation of Kato's main conjecture for f over the Zp-cyclotomic extension of Q.
Antonio Lei
core +2 more sources
On Diophantine approximation by unlike powers of primes
Suppose that λ1, λ2, λ3, λ4, λ5 are nonzero real numbers, not all of the same sign, λ1/λ2 is irrational, λ2/λ4 and λ3/λ5 are rational. Let η real, and ε > 0.
Ge Wenxu, Li Weiping, Wang Tianze
doaj +1 more source
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
On the locus of priming and inverse priming effects [PDF]
Visual stimuli that are made invisible by a following mask can affect overt motor responses and nonmotor processing. Previous studies have compared the effects of primes that were perceptually similar to the subsequent stimulus with those of primes that were perceptually similar to an alternative stimulus.
openaire +3 more sources
‘Fell’ primes ‘fall’, but does ‘bell’ prime ‘ball’? Masked priming with irregularly-inflected primes [PDF]
Abstract Recent masked priming experiments have brought to light a morphological level of analysis that is exclusively based on the orthographic appearance of words, so that it breaks down corner into corn- and -er, as well as dealer into deal- and -er ( Rastle, Davis, & New, 2004 ).
Crepaldi, Davide +3 more
openaire +3 more sources
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source

