Results 71 to 80 of about 32,275 (267)
miR-125b develops chemoresistance in Ewing sarcoma/primitive neuroectodermal tumor
BackgroundDiverse functions of microRNAs (miRNAs), including effects on tumorigenesis, proliferation, and differentiation, have been reported, and several miRNAs have also been demonstrated to play an important role in apoptosis.
K. Iida +10 more
semanticscholar +1 more source
Anticancer Molecular Mechanisms of Curcuminoids: An Updated Review of Clinical Trials
Curcuminoids remain one of the most studied dietary polyphenols as a cancer prevention and treatment agent. Inflammation and tumor progression are related to the NF‐κB signaling pathway, which is also suppressed by curcuminoids. Curcuminoids prevent the activation of a variety of signaling pathways, including the MAPK, PI3K/Akt, and NF‐kB pathways ...
Ushna Momal +14 more
wiley +1 more source
Mutations in the RB1 Gene in Argentine Retinoblastoma Patients and Uncommon Clinical Presentations [PDF]
Background: Retinoblastoma, the most common ocular cancer of childhood, is caused by inactivation of the RB1 tumor suppressor gene in the developing retina.
Alonso, Cristina +6 more
core +1 more source
We present a case of a 42‐year‐old woman presenting with pleural effusion, a rare manifestation of Ewing sarcoma. ABSTRACT Extraskeletal Ewing sarcoma (EES) is a rare malignant tumour within the “Ewing family of tumours,” first described by Tefft et al. in 1969.
Hamza Khan Khattak +6 more
wiley +1 more source
High grade primitive neuroectodermal tumor of the uterus: A case report☆
Highlights • Primitive neuroectodermal tumor of the uterus is extremely rare.• Diagnosis requires timely evaluation with molecular analysis.• Different combinations of adjuvant chemotherapy have been reported.
A. Dizon +4 more
semanticscholar +1 more source
ABSTRACT Chest‐wall Ewing sarcoma (CWES) is uncommon in adults and often abuts vital thoracic structures, making R0 resection challenging despite gains with multimodal therapy. A 46‐year‐old Arab male presented with year‐long right‐sided chest pain, weight loss, and a firm mass over the lower right ribs.
Mohammad Alaa Aldakak +5 more
wiley +1 more source
Ewing Family Tumors: Potential Prognostic Value of Reverse-Transcriptase Polymerase Chain Reaction Detection of Minimal Residual Disease in Peripheral Blood Samples [PDF]
In more than 95% of patients, the Ewing family of tumors (ET) has chimeric transcripts caused by fusion of the EWS gene to either FLI1 or ERG. The presence of specific EWS-FLI1 or EWS-ERG transcripts in peripheral blood (PB) samples of
Alava, E. (Enrique) de +4 more
core
Scrotal Peripheral Primitive Neuroectodermal Tumor
The peripheral primitive neuroectodermal tumor (pPNET) is a rare malignant tumor originating from neuroectoderm that usually occurs in children or adolescent and is frequently located in the extremities, chest cavity, pelvic cavity and chest wall. We present a rare case of an 84-year-old man with a history of pPNET in the scrotal sac, to our knowledge ...
Sandra, Baleato-González +3 more
openaire +2 more sources
Sunitinib malate (Sutent™; Pfizer Inc., New York, N.Y., USA) is a small molecule kinase inhibitor with activity against a number of tyrosine kinase receptors, including vascular endothelial growth factor receptors, stem-cell factor receptor, and platelet-
T. Prochilo +6 more
semanticscholar +1 more source
Our results support that low grade glial tumours of germ cell origin (LGGTs) represent a phenomenon of maturation (either spontaneous or induced by therapy) of embryonic‐type neuroectoderm, being possibly equivalent to teratoma from a biological perspective.
João Lobo +10 more
wiley +1 more source

