Results 41 to 50 of about 14,338 (204)

Adipocyte-Like Differentiation in a Posttreatment Embryonal Rhabdomyosarcoma. [PDF]

, 2015
We describe a 16-year-old boy with rhabdomyosarcoma, consistent with embryonal subtype, of the lower extremity who received systemic neoadjuvant chemotherapy and subsequent excision.
Balitzer, Dana, Horvai, Andrew E, McCalmont, Timothy H   +2 more
core   +9 more sources

Tumor classification: molecular analysis meets Aristotle [PDF]

, 2004
Background Traditionally, tumors have been classified by their morphologic appearances. Unfortunately, tumors with similar histologic features often follow different clinical courses or respond differently to chemotherapy.
Jules J Berman, J Rosai, E Mayr, MB Eisen, A Rosenwald, S Ramaswamy, W Weyers, TR Golub, R Capdeville, GT Diamandopoulos, P Kleihues, RA Willis, SL Cohn, SJ Gould, K Thiele, JM Logsdon, M Martine Peter, WN Hittelman, I Bongarzone, JC Jensen, LM DeAngelis, B Skogseid, T Nakamura, J Nishio, AK Anand, M Peoch, SK Sidhar, LR Essary, MC Aubry, JD Seidman   +29 more
core   +2 more sources

A molecular biology and phase II trial of lapatinib in children with refractory CNS malignancies: a pediatric brain tumor consortium study. [PDF]

, 2013
High expression of ERBB2 has been reported in medulloblastoma and ependymoma; EGFR is amplified and over-expressed in brainstem glioma suggesting these proteins as potential therapeutic targets. We conducted a molecular biology (MB) and phase II study to
Blaney, Susan M., Boyett, James M., Fouladi, Maryam, Gajjar, Amar, Geyer, J. Rusell, Gilbertson, Richard J., Goldman, Stewart, Kun, Larry E., Onar Thomas, Arzu, Packer, Roger J., Schaiquevich, Paula Susana, Stewart, Clinton F.   +11 more
core   +1 more source

Embryonic Tumor with Abundant Neuroepithelium and True Rosettes (ETANTR): Case Report and Literature Review

Brazilian Neurosurgery, 2017
The embryonal tumor with abundant neuropil and true rosettes (ETANTR) is an extremely rare variant of the primitive neuroectodermal tumor (PNET). About 80 cases have been reported since its first description in the literature, in 2000.
Cleciton Braga Tavares, Francisca das Chagas Sheyla Almeida Gomes-Braga, Emerson Brandão Sousa, Camilla Aniele Areia Ferreira, José Nazareno Pearce de Oliveira Brito   +4 more
doaj   +1 more source

Skull Base Surgery in the Pediatric Population—The 2nd International Collaborative Study (1995–2015)

Head &Neck, EarlyView.
ABSTRACT Background The current study presents the efforts of a global collaborative group to review the management and outcomes of malignant tumors of the skull base in the pediatric population worldwide. Patients and Methods A total of 28 institutions contributed data on 3061 patients. From this, there were 64 pediatric patients (2.1%).
Dan M. Fliss, Omer J. Ungar, Helena Levyn, Cristina Valero, Dauren Adilbay, Alana Eagan, Junting Zheng, Mithat Gonen, Marc A. Cohen, Snehal Patel, Ian Ganly, Prathamesh Pai, Paolo Castelnuovo, Fang Ju Gao, Cesare Piazza, Piero Nicolai, Benedict J. Panizza, James Bowman, Catherine Barnett, Luiz P. Kowalski, Ronaldo N. Toledo, John DeAlmeida, Ian Witterick, Philippe Herman, Walter Fontanella, Gregorio Sanchez Aniceto, Sefik Hosal, Serdar Ozer, Subramania Iyer, Richard Harvey, C. Rene Leemans, Jan‑Jaap Hendrickx, Marcelo Figari, Luis Boccalatte, Ichi Nibu, Peter Clarke, Catherine Rennie, Yiming Zhu, Claudio Cernea, Sergio Goncalves, Rodney Schlosser, Fernando Dias, Zoukaa Sargi, Shahzada Ahmed, Wojciech Golusinski, Se Heon Kim, Shirley Y. Su, Shaan M. Raza, Franco DeMonte, Ehab Hanna, Jatin P. Shah   +50 more
wiley   +1 more source

Primitive neuroectodermal tumor of maxilla in a 4-year-old child: A rare case report with update on molecular pathogenesis

Indian Journal of Dental Sciences, 2022
Primitive neuroectodermal tumor (PNET) belongs to the class of malignant round cell tumor. PNETs show varying degree of neuroectodermal differentiation.
Pavan Patil, Mithilesh Narayan Mishra, Vidyadevi Chandavarkar, Seema Pavan Patil   +3 more
doaj   +1 more source

Molecular dissection of the mechanism by which EWS/FLI expression compromises actin cytoskeletal integrity and cell adhesion in Ewing sarcoma. [PDF]

, 2014
Ewing sarcoma is the second-most-common bone cancer in children. Driven by an oncogenic chromosomal translocation that results in the expression of an aberrant transcription factor, EWS/FLI, the disease is typically aggressive and micrometastatic upon ...
Beckerle, Mary C, Chaturvedi, Aashi, Grossmann, Allie H, Hoffman, Laura M, Jensen, Christopher C, Lessnick, Stephen L, Lin, Yi-Chun, Randall, R Lor, Welm, Alana L   +8 more
core   +1 more source

Comparison of Auto‐Contouring Tools for Delineation of Normal Organs at Risk in Paediatric Patients Undergoing Radiotherapy

Journal of Medical Radiation Sciences, EarlyView.
Contouring organs at risk (OARs) manually in paediatric patients undergoing cranial‐spinal radiation therapy (CSI) is a time‐consuming, labour‐intensive task. This study aims to assess the accuracy and clinical acceptability of auto‐contours produced by the Siemens DirectORGANS auto‐contouring software on paediatric patients receiving CSI treatment ...
Isabel Cant, Jonathan Sykes, Yolanda Surjan, Rachael Beldham‐Collins, Laura Murphy, John Fernandez, Alison Salkeld   +6 more
wiley   +1 more source

Target cells of human adenovirus type 12 in subtentorial brain tissue of newborn mice. I. Cyto-histomorphologic and immunofluorescent microscopic studies In vivo [PDF]

, 1976
Human adenovirus type 12 (Ad 12) was inoculated through subtentorial route into inbred newborn mice (C3H/BifB/Ki), and sequential changes of the brain and tumor induction were examined by histological and immunofluorescent methods.
Athanasiou, T, Barrett, H, Camelliti, P, Pinto, K, Prodromakis, T, Rao, C, Terracciano, CM, Toumazou, C, Trantidou, T, Yacoub, MH   +9 more
core   +1 more source

Integrated high‐resolution copy number and histomolecular analysis of diffuse hemispheric glioma, H3 G34‐mutant reveals universal TP53 abnormalities

Brain Pathology, EarlyView.
This integrated high‐resolution copy number and histomolecular analysis of diffuse hemispheric glioma, H3 G34‐mutant expands the spectrum of associated genetic changes and underscores the presence of universal TP53 abnormalities at copy number, sequence, and protein expression level, with frequent yet largely unrecognized TP53 copy‐neutral loss of ...
Jorge A. Trejo‐Lopez, Cinthya Zepeda Mendoza, Thomas M. Kollmeyer, Kristen L. Drucker, Vanessa M. Pazdernik, Paul A. Decker, Corinne E. Praska, Jayson Hardcastle, Stephanie Smoley, Matthew Isaacson, Mallika Gandham, Surendra Dasari, Aditya Raghunathan, Caterina Giannini, Gang Zheng, Aaron Wagner, M. Beatriz Lopes, Kar‐Ming A. Fung, JoElle G. Peterson, Andreana L. Rivera, Christopher Rossi, Meggen A. Walsh, Zied Abdullaev, Kenneth Aldape, Martha Quezado, Drew Pratt, Patrick Joseph Cimino, Robert B. Jenkins, Cristiane M. Ida   +28 more
wiley   +1 more source