Results 51 to 60 of about 5,174 (227)
MTAP Deficiency as a Metabolic Vulnerability in Cancer: Implications for Synthetic Lethal Therapy
Cancer Science, EarlyView.MTAP deletion creates a therapeutically actionable metabolic vulnerability through MTA accumulation and PRMT5 dependency. This review summarizes the biochemical basis of MTAP‐directed synthetic lethality, emerging PRMT5/MAT2A inhibitors, clinicogenomic features of MTAP‐deleted tumors, and future strategies for precision oncology.
Hiroaki Ikushima, Hidenori Kage
wiley +1 more source
Primula farinosa Linnaeus 1753
, 2007 Primula farinosa Linnaeus, Species Plantarum 1: 143. 1753. "Habitat in Alpinis frigidisque Europae pratis uliginosis." RCN: 1151. Lectotype (Halda, Genus Primula: 244. 1992): Herb. Linn. No. 198.7 (LINN).
Jarvis, Charlie
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, 1879 Sur les Primula hybrides. In: Annales de la Société botanique de Lyon, tome 6, Compte-rendu des séances – 1877-1878. 1879. pp.
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Genus Primula and its role in phytomedicine; a systematic review
Phytomedicine PlusBackground: Primula is one of the prevalent and complex genus of family Primulaceae. Plants of Genus Primula are used in traditional medicine for treating various ailments. These plants are mostly growing in soggy meadows to alpine slopes.
Fiaz Alam +4 more
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Diversification of Exudate Flavonoid Profiles in Further
Natural Product Communications, 2012 In continuation of previous work, exudate flavonoid profiles of 22 new accessions of the genus Primula L. aligned to different subgenera were studied for the first time. Profiling was done by comparative TLC and UV-HPLC against authentic marker compounds.
Tshering Doma Bhutia +1 more
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Primula vulgaris extract induces cell cycle arrest and apoptosis in human cervix cancer cells
Journal of Pharmaceutical Analysis, 2018 Primula vulgaris belongs to the genus Primula, members of which are frequently used in folk medicine. Various studies have investigated the cytotoxic effect of different Primula species, but there have been limited studies on the cytotoxic effect of P ...
Selim Demir +4 more
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Contact Dermatitis, EarlyView.ABSTRACT The present guideline updates the initial ESCD patch testing guideline, summarizing all aspects of patch testing for the diagnosis of contact allergy in patients suspected of suffering, or having been suffering, from allergic contact dermatitis or other delayed‐type hypersensitivity skin and mucosal conditions. Sections with brief descriptions
Wolfgang Uter +23 more
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Acta Agrobotanica, 2013 The severe winter which occurred in Poland in 1986-1987 damaged the most part of scab resistant apple cultivars and selected apple hybrids. Cold hardiness studied in 1987 and 1988 showed significant differences in degree of frost injury on stem, branches,
Zbigniew Borecki +4 more
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JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.Summary This second part of the S3 guideline on the diagnosis and treatment of alopecia areata (AA), presents key recommendations on topical and systemic therapy, quality of life and support services. The first part of the guideline, published separately, covers the definition and content of epidemiology and diagnosis as well as comorbidities, risk and
Ulrike Blume‐Peytavi +13 more
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Typification of Primula nivalis Pall.
, 2014 The herbarium material that was the basis for Primula nivalis, described by Simon Pallas in 1776, and held at the Natural History Museum in London, is discussed, and a lectotype of Primula nivalis is ...
Charles E. Jarvis, Nataliya K. Kovtonyuk
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