Results 61 to 70 of about 799,212 (303)

Incentives Research for Enterprises to Participate in VEP in the Multitask Principal-Agent Model

open access: yesSHS Web of Conferences, 2015
As a comprehensive environmental management system with a higher statutory environmental standard, Voluntary Environmental Program has become a trend of international environmental policy and the essence of it is a multi-agency task, in which government (
Mo Sha, Shi Xiaoping
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Optimal time-based and cost-based contracts in construction projects under asymmetric information

open access: yesJournal of Civil Engineering and Management
A project owner (principal) delegates a project to a contractor (agent). Because the contractor has construction experience, he has private information about the project’s expected completion time.
Guanqun Shi   +3 more
doaj   +1 more source

Principle – Agent Model for Sleeping Partnership Moral hazard [PDF]

open access: yesFaslnāmah-i Pizhūhish/Nāmah-i Iqtisādī, 2011
Game theory has a significant role in contemporary orthodox economics. This theory studies the strategic behavior of players. So strategic interaction is the key point in the games theory.  Principalagent model is an application of the theory. This model
Mohammad Hadi Zahidi Vafa   +1 more
doaj  

The role of histone modifications in transcription regulation upon DNA damage

open access: yesFEBS Letters, EarlyView.
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley   +1 more source

Mechanisms of parasite‐mediated disruption of brain vessels

open access: yesFEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira   +3 more
wiley   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

A Solvable Time-Inconsistent Principal-Agent Problem

open access: yesDiscrete Dynamics in Nature and Society, 2018
We consider the dynamic contract model with time inconsistency preference of principal-agent problem to study the influence of the time inconsistency preference on the optimal effort and the optimal reward mechanism.
Chao Li, Zhijian Qiu
doaj   +1 more source

Government subsidies in public-private partnership projects based on altruistic theory

open access: yesInternational Journal of Strategic Property Management, 2020
Nowadays, the public-private partnership (PPP) scheme has been widely adopted in infrastructure projects around the world. In PPP projects, the governments participate as a principal and the investors play the role of an agent, and therefore their ...
Yinglin Wang   +3 more
doaj   +1 more source

Job Design and Randomization in Principal Agent Models [PDF]

open access: yesSSRN Electronic Journal, 2008
We analyze task allocation and randomization in Principal Agent models. We identify a new rationale that determines the allocation of tasks and show that it can be optimal to assign tasks that are very different to one agent. Similar to randomization, the reason to assign several tasks to one agent is to mitigate the effect of the participation ...
openaire   +2 more sources

Home - About - Disclaimer - Privacy