Results 151 to 160 of about 658,976 (287)

The Role of the Agent's Outside Options in Principal-Agent Relationships [PDF]

We consider a principal-agent model of adverse selection where, in order to trade with the principal, the agent must undertake a relationship-specific investment which affects his outside option to trade, i.e.
Imran Rasul, Silvia Sonderegger
core  

Implementation of Drug‐Induced Rhabdomyolysis and Acute Kidney Injury in Microphysiological System

Advanced Functional Materials, EarlyView.
A modular Muscle–Kidney proximal tubule‐on‐a‐chip integrates 3D skeletal muscle and renal proximal tubule tissues to model drug‐induced rhabdomyolysis and acute kidney injury. The coculture system enables dynamic tissue interaction, functional contraction monitoring, and quantification of nephrotoxicity, revealing drug side effect‐induced metabolic ...
Jaesang Kim, Zhuo Feng Lee, Gi‐Dong Sim, Sejoong Kim, Jessie S. Jeon   +4 more
wiley   +1 more source

Smart, Bio‐Inspired Polymers and Bio‐Based Molecules Modified by Zwitterionic Motifs to Design Next‐Generation Materials for Medical Applications

Advanced Functional Materials, EarlyView.
Bio‐based and (semi‐)synthetic zwitterion‐modified novel materials and fully synthetic next‐generation alternatives show the importance of material design for different biomedical applications. The zwitterionic character affects the physiochemical behavior of the material and deepens the understanding of chemical interaction mechanisms within the ...
Theresa M. Lutz, Jonas De Breuck, Sahar Salehi, Meike N. Leiske   +3 more
wiley   +1 more source

Comparing machine learning, deep learning, and reinforcement learning performance in Culex pipiens predictive modeling. [PDF]

PLoS One
Yin W, Ragab SH, Tyshenko MG, Arroyo TF, Oraby T.   +4 more
europepmc   +1 more source

Do Elections Always Motivate Incumbents?. [PDF]

This paper studies a principal-agent model of the relationship between office-holders and the electorate, where the office-holder is initially uninformed about herability (following Holmström, 1999).
le Borgne, E., Lockwood, B.
core  

Unleashing the Power of Machine Learning in Nanomedicine Formulation Development

Advanced Functional Materials, EarlyView.
A random forest machine learning model is able to make predictions on nanoparticle attributes of different nanomedicines (i.e. lipid nanoparticles, liposomes, or PLGA nanoparticles) based on microfluidic formulation parameters. Machine learning models are based on a database of nanoparticle formulations, and models are able to generate unique solutions
Thomas L. Moore, Cristiano Pesce, Antonietta Greco, Claudia Pisante, Greta Avancini, Valentina Di Francesco, Yosi Shamay, Paolo Decuzzi   +7 more
wiley   +1 more source

Add-on combination therapy with monoclonal antibodies: Implications for drug development. [PDF]

J Prev Alzheimers Dis
Cummings J, Burstein AH, Fillit H.
europepmc   +1 more source

Photonic Engineering Enables All‐Passive Upconversion Imaging with Low‐Intensity Near‐Infrared Light

Advanced Functional Materials, EarlyView.
A passive upconversion imaging system enables the observation of scenes illuminated by low‐intensity incoherent near‐infrared light from 750 to 930 nm, by converting it into the visible without the use of external power. The upconverter is enabled by triplet–triplet annihilation in a bulk heterojunction, with absorption enhanced by plasmonic resonators
Rabeeya Hamid, Demeng Feng, Pournima Narayanan, Justin S. Edwards, Manchen Hu, Emma Belliveau, Minjeong Kim, Shenwei Yin, Sanket Deshpande, Chenghao Wan, Linda Pucurimay, David A. Czaplewski, Daniel N. Congreve, Mikhail A. Kats   +13 more
wiley   +1 more source

Low friction layer in sanitary products for reduced skin irritation. [PDF]

Sci Rep
Nishi T, Matsui K, Ito R, Kuramochi M, Fujita M, Yamaguchi T.   +5 more
europepmc   +1 more source

Task-specific effort costs and the trade-off between risk and efficiency [PDF]

This paper considers a principal-agent model in which an agent chooses the level of effort on two tasks that determine two separate outputs. The level of effort is private information to the agent.
Marisa Ratto
core