Results 71 to 80 of about 8,580,386 (306)

The Application of The Agency Theory In Planning And Staff Assignment of CPA Firms [PDF]

open access: yesبررسی‌های حسابداری و حسابرسی, 1994
This article extends the concept of agency theory to multi-objective contractual settings and operationalizes the elements of the basic agency model by applying that model to the operations of a CPA firm, and specifying the pareto-optimal contracts that ...
Dr. Mohammad Narnazi
doaj  

The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer

open access: yesMolecular Oncology, EarlyView.
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad   +2 more
wiley   +1 more source

Principal-Agent Problem with Minimum Performance Insurance [PDF]

open access: yes
A minimum performance insurance in the Principal-Agent problem is wealth reducing to the principal. This result points to further inefficiencies in mandatory individual Pension Funds' contracts, particularly the one established in the 1993's 100th Law in
Juan Manuel Julio
core  

Principal-agent boolean games

open access: yes, 2023
We introduce and study a computational version of the principal-agent problem - a classic problem in Economics that arises when a principal desires to contract an agent to carry out some task, but has incomplete information about the agent or their ...
David Hyland (21537970)   +2 more
core  

Regulation of the lncRNA NEAT1 by p53‐ΔNp63 crosstalk modulates the DNA damage response and therapeutic efficacy in HNSCC

open access: yesMolecular Oncology, EarlyView.
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico   +5 more
wiley   +1 more source

Setting Incentives for Collaboration Among Agricultural Scientists: Application of Principal-Agent Theory to Team Work [PDF]

open access: yes
The USDA is attempting to shift more research funds into competitive grants involving collaboration across disciplines on large projects. This type of research structure raises a host of information and incentive issues.
Wallace E. Huffman
core  

How Supervision Failures Lead to Quality Risk of Land Trusteeship Services: A Principal–Agent Theory Perspective

open access: yesLand
The service quality of land trusteeship is often subpar due to farmers’ ineffective supervision of service providers’ opportunistic behaviors. However, the existing literature has not given much attention to this agency issue from the principal–agent ...
Lianghong Yu, Shan Zheng, Kun Gao
doaj   +1 more source

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

open access: yesMolecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez   +5 more
wiley   +1 more source

A Principal-Agent Analysis of the Family: Implications for the Welfare State [PDF]

open access: yes
The principal-agent literature has focussed on situations where both principal and agent are assumed to be capable of defining and defending their own interests.
Munro, Lauchlan
core  

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