Developmental, Neuroanatomical and Cellular Expression of Genes Causing Dystonia
ABSTRACT Objective Dystonia is one of the most common movement disorders, with variants in multiple genes identified as causative. However, an understanding of which developmental stages, brain regions, and cell types are most relevant is crucial for developing relevant disease models and therapeutics.
Darren Cameron +5 more
wiley +1 more source
Does in-bed cycling delivered within 48 hours of mechanical ventilation, reduce the occurrence of delirium in critically ill patients: A mixed-methods feasibility randomised controlled trial protocol. [PDF]
Bennion J +6 more
europepmc +1 more source
Objective Imaging evidence of active sacroiliitis is important for diagnosis, classification, and monitoring of axial spondyloarthritis (axSpA). However, there is no consistent guidance on whether patients should temporarily stop nonsteroidal anti‐inflammatory drugs (NSAIDs) before magnetic resonance imaging (MRI).
Gareth T. Jones +10 more
wiley +1 more source
LHFPL5 is required for maximal activation of the mechanotransduction channel in cochlear hair cells. [PDF]
Qiu X +4 more
europepmc +1 more source
Development and External Validation of a Genetic Risk Score for Pain in Rheumatoid Arthritis
Objective Several single‐nucleotide polymorphisms (SNPs) have been associated with chronic pain syndromes. Our objective was to determine whether genetic variants are associated with pain and disease activity in rheumatoid arthritis (RA). Methods Participants were included from two independent RA cohorts: FORWARD (National Databank for Rheumatic ...
Katie J. McMenamin +15 more
wiley +1 more source
A new preclinical sheep model of medial meniscus anterior root repair: Part 1-Quantitative morphology and relationships to adjacent structures. [PDF]
Liu W +5 more
europepmc +1 more source
Objectives This study aims to describe the frequency and timing of physician referrals to physical therapists (PT) and other treatments prescribed over 12 months in patients with recent onset of knee osteoarthritis (KOA). The study also aims to identify determinants of early PT referrals.
Samannaaz S. Khoja +4 more
wiley +1 more source
Assessing the Cost-effectiveness of Pressure Injury Prevention Strategies in a Quasi-experimental Design. [PDF]
Asiri MY +3 more
europepmc +1 more source
Objectives This study aimed to identify the frequency and determinants of Lupus Low Disease Activity State (LLDAS) and Definition of Remission in SLE (DORIS‐remission) attainment in systemic lupus erythematosus (SLE) patients with clinically active disease, and the frequency and determinants of flare and damage accrual after target attainment.
Yanjie Hao +39 more
wiley +1 more source
Moduli of curves with principal and spin bundles : singularities and global geometry
Mattia Francesco Galeotti
openalex +1 more source

