Results 71 to 80 of about 198,779 (330)

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

open access: yesFEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang   +8 more
wiley   +1 more source

Exotic spheres’ metrics and solutions via Kaluza-Klein techniques

open access: yesJournal of High Energy Physics, 2023
By applying an inverse Kaluza-Klein procedure, we provide explicit coordinate expressions for Riemannian metrics on two homeomorphic but not diffeomorphic spheres in seven dimensions.
T. Schettini Gherardini
doaj   +1 more source

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

open access: yesFEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang   +9 more
wiley   +1 more source

Geometry of frame bundles

open access: yesLietuvos Matematikos Rinkinys
In this article we define the canonical forms on the principal bundle of holonomic frames of order r, give structure equations for these forms and determine the connection of order r.
Kazimeras Navickis
doaj   +3 more sources

Сurvature-torsion tensor for Cartan connection

open access: yesДифференциальная геометрия многообразий фигур, 2019
A Lie group containing a subgroup is considered. Such a group is a principal bundle, a typical fiber of this principal bundle is the subgroup and a base is a homogeneous space, which is obtained by factoring the group by the subgroup.
Yu. Shevchenko
doaj   +1 more source

On 2-Holonomy

open access: yes, 2012
We construct a cycle in higher Hochschild homology associated to the 2-dimensional torus which represents 2-holonomy of a non-abelian gerbe in the same way the ordinary holonomy of a principal G-bundle gives rise to a cycle in ordinary Hochschild ...
Baez   +11 more
core   +1 more source

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

open access: yesFEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

Differential geometry of collective models

open access: yesAIMS Mathematics, 2019
The classical astrophysical theory of Riemann ellipsoids and the quantum nuclear theory of Bohr and Mottelson share a common mathematical foundation in terms of the differential geometry of a principal bundle ${\cal P}$ and its associated vector bundle E,
George Rosensteel
doaj   +1 more source

Four Equivalent Versions of Non-Abelian Gerbes

open access: yes, 2013
We recall and partially improve four versions of smooth, non-abelian gerbes: Cech cocycles, classifying maps, bundle gerbes, and principal 2-bundles. We prove that all these four versions are equivalent, and so establish new relations between interesting
Nikolaus, Thomas, Waldorf, Konrad
core   +1 more source

Principal bundles on the projective line

open access: yesProceedings Mathematical Sciences, 2002
Let \(G\) be a reductive group defined over any field \(k\) of characteristic different from \(2\) and \(3\). Let \(E\) denote a principal \(G\)-bundle on the projective line \({\mathbb P}^1_k\) which is trivial at the origin i.e., the restriction of \(E\) to the \(k\)-rational point \(0\in {\mathbb P}^1_k\) is a trivial principal homogeneous space ...
Mehta, V. B., Subramanian, S.
openaire   +2 more sources

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