Results 71 to 80 of about 200,533 (263)

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

open access: yesFEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang   +8 more
wiley   +1 more source

Diffeological principal bundles and principal infinity bundles

open access: yesJournal of Homotopy and Related Structures
In this paper, we study diffeological spaces as certain kinds of discrete simplicial presheaves on the site of cartesian spaces with the coverage of good open covers. The Čech model structure on simplicial presheaves provides us with a notion of $\infty$-stack cohomology of a diffeological space with values in a diffeological abelian group $A$.
openaire   +2 more sources

Geometry of quantum principal bundles I [PDF]

open access: yesCommunications in Mathematical Physics, 1996
A general non-commutative-geometric theory of principal bundles is developed. Quantum groups play the role of structure groups and general quantum spaces play the role of base manifolds. A general conceptual framework for the study of differential structures on quantum principal bundles is presented.
openaire   +4 more sources

On 2-Holonomy

open access: yes, 2012
We construct a cycle in higher Hochschild homology associated to the 2-dimensional torus which represents 2-holonomy of a non-abelian gerbe in the same way the ordinary holonomy of a principal G-bundle gives rise to a cycle in ordinary Hochschild ...
Baez   +11 more
core   +1 more source

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

open access: yesFEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang   +9 more
wiley   +1 more source

Exotic spheres’ metrics and solutions via Kaluza-Klein techniques

open access: yesJournal of High Energy Physics, 2023
By applying an inverse Kaluza-Klein procedure, we provide explicit coordinate expressions for Riemannian metrics on two homeomorphic but not diffeomorphic spheres in seven dimensions.
T. Schettini Gherardini
doaj   +1 more source

Pullback of quantum principal bundles [PDF]

open access: green, 2022
Francesco D’Andrea, Tomasz Maszczyk
openalex   +1 more source

Translation map in quantum principal bundles

open access: yes, 1996
The notion of a translation map in a quantum principal bundle is introduced. A translation map is then used to prove that the cross sections of a quantum fibre bundle $E(B,V,A)$ associated to a quantum principal bundle $P(B,A)$ are in bijective ...
Booss   +23 more
core   +1 more source

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

open access: yesFEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

Geometry of frame bundles

open access: yesLietuvos Matematikos Rinkinys
In this article we define the canonical forms on the principal bundle of holonomic frames of order r, give structure equations for these forms and determine the connection of order r.
Kazimeras Navickis
doaj   +3 more sources

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