Results 91 to 100 of about 2,300,147 (337)

Lazy stochastic principal component analysis

open access: yes, 2017
Stochastic principal component analysis (SPCA) has become a popular dimensionality reduction strategy for large, high-dimensional datasets. We derive a simplified algorithm, called Lazy SPCA, which has reduced computational complexity and is better ...
Li, Li   +3 more
core   +1 more source

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

open access: yesFEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang   +8 more
wiley   +1 more source

High Dimensional Semiparametric Scale-Invariant Principal Component Analysis

open access: yes, 2014
We propose a new high dimensional semiparametric principal component analysis (PCA) method, named Copula Component Analysis (COCA). The semiparametric model assumes that, after unspecified marginally monotone transformations, the distributions are ...
Han, Fang, Liu, Han
core   +1 more source

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

open access: yesFEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang   +9 more
wiley   +1 more source

PRINCIPAL COMPONENT ANALYSIS (PCA) DAN APLIKASINYA DENGAN SPSS

open access: yesJurnal Kesehatan Masyarakat Andalas, 2009
PCA (Principal Component Analysis ) are statistical techniques applied to a single set of variables when the researcher is interested in discovering which variables in the setform coherent subset that are relativity independent of one another.Variables ...
Hermita Bus Umar
doaj   +1 more source

Use of Principal Component Analysis and Cluster Analysis for Differentiation of Traditionally-Manufactured Vinegars Based on Phenolic and Volatile Profiles, and Antioxidant Activity

open access: yesPolish Journal of Food and Nutrition Sciences, 2020
This study aimed to characterize twelve vinegar samples produced by the traditional method with the use of whole fruits and without any preservatives in terms of their physicochemical properties, total phenolic content (TPC), total flavonoid content (TFC)
Ayse Karadag   +3 more
doaj   +1 more source

Principal Component Analysis of RR Lyrae light curves

open access: yes, 2004
In this paper, we analyze the structure of RRab star light curves using Principal Component Analysis. We find this is a very efficient way to describe many aspects of RRab light curve structure: in many cases, a Principal Component fit with 9 parameters ...
H. Mariani   +8 more
core   +3 more sources

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

open access: yesFEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

Statistical and computational techniques for extraction of underlying systematic risk factors: a comparative in the Mexican stock exchange

open access: yesRevista Finanzas y Política Económica, 2021
This paper compares the dimension reduction or feature extraction techniques, e.g., Principal Component Analysis, Factor Analysis, Independent Component Analysis and Neural Networks Principal Component Analysis, which are used as techniques for ...
Rogelio   +2 more
doaj  

A spatiotemporal assessment of the high-resolution CHIRPS rainfall dataset in southwestern Colombia using combined principal component analysis

open access: gold, 2022
Camilo Ocampo-Marulanda   +5 more
openalex   +1 more source

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