Results 151 to 160 of about 26,519,848 (254)

Localized Sparse Principal Component Analysis of Multivariate Time Series in the Frequency Domain. [PDF]

J Am Stat Assoc
Namdari J, Manatunga A, Ferrarelli F, Krafty RT.   +3 more
europepmc   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

Multivariate Neuromuscular Profile and Principal Component Analysis: A Pilot Study in Professional Female Soccer Players. [PDF]

Life (Basel)
Romero-Vera L, Ulloa-Díaz D, Concha-Poblete J, Sandoval-Cárcamo M, Carvajal-Parodi C, Guede-Rojas F, Jorquera-Aguilera C, Ulloa-Barboza C, Hernández-Mosqueira C, Pavez-Adasme G, Guzmán-Muñoz E, Fuentes-Barría H, Leschot-Gatica J.   +12 more
europepmc   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

Functional quantile principal component analysis. [PDF]

Biostatistics
Méndez-Civieta Á, Wei Y, Diaz KM, Goldsmith J.   +3 more
europepmc   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

The pls Package: Principal Component and Partial Least Squares Regression in R [PDF]

The pls package implements principal component regression (PCR) and partial least squares regression (PLSR) in R (R Development Core Team 2006b), and is freely available from the Comprehensive R Archive Network (CRAN), licensed under the GNU General ...
Björn-Helge Mevik, Ron Wehrens
core  

Disease progression modeling of Alzheimer's disease based on variational probability principal component analysis. [PDF]

PLoS One
Xiong X, Wang X, Zhu C, He J, Alzheimer’s Disease Neuroimaging Initiative.   +4 more
europepmc   +1 more source

Flow Enabled Target Capture Halbach‐based magnetic enrichment increases circulating tumor cell capture from blood in metastatic cancer patients

Molecular Oncology, EarlyView.
Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens, Anouk Mentink, Tom Niessink, Frank Coumans, Leonie Mekenkamp, Ruchi Bansal, Jeroen Hiltermann   +6 more
wiley   +1 more source

Lithological identification for mixed carbonate and clay sediments employing principal component analysis of geophysical logging. [PDF]

Sci Rep
Guo J, Wang L, Li Y, Wang Y, Zhou L.
europepmc   +1 more source