Results 261 to 270 of about 2,775,431 (371)

The Use of Neural Networks, Principal Component Analysis and Universal Process Modeling for the Interpretation of Environmental Data [PDF]

, 1996
Devon A. Cancilla, Xingchun Fang
openalex   +1 more source

Beyond digital twins: the role of foundation models in enhancing the interpretability of multiomics modalities in precision medicine

FEBS Open Bio, EarlyView.
This review highlights how foundation models enhance predictive healthcare by integrating advanced digital twin modeling with multiomics and biomedical data. This approach supports disease management, risk assessment, and personalized medicine, with the goal of optimizing health outcomes through adaptive, interpretable digital simulations, accessible ...
Sakhaa Alsaedi, Xin Gao, Takashi Gojobori   +2 more
wiley   +1 more source

Principal component analysis revisited: fast multitrait genetic evaluations with smooth convergence. [PDF]

G3 (Bethesda)
Ahlinder J, Hall D, Suontama M, Sillanpää MJ.   +3 more
europepmc   +1 more source

Acacetin reduces endoplasmic reticulum stress through the P‐eNOS/PERK signaling pathway to attenuate MGO‐induced vascular endothelial cell dysfunction

FEBS Open Bio, EarlyView.
We investigated a potential protective effect of acacetin, a naturally occurring flavonoid, against methylglyoxal (MGO)‐induced endothelial dysfunction in human umbilical vein endothelial cells and its mechanism of action. Acacetin can could inhibit MGO‐induced intracellular calcium ion influx, enhance the expression levels of phosphorylated ...
Zhen Zhang, Kaien Hu, Zhaohui Fang, Sihai Wang, Jie Chen, Dengke Yin, Caiyun Zhang, Gefei Ma   +7 more
wiley   +1 more source

Applying genetic algorithm to extreme learning machine in prediction of tumbler index with principal component analysis for iron ore sintering. [PDF]

Sci Rep
Wang S.
europepmc   +1 more source

Red blood cells could protect miRNAs from degradation or loss thanks to Argonaute 2 binding

FEBS Open Bio, EarlyView.
The present work investigates the presence and the stability of miRNAs into RBCs, both native and engineered. The observed stability is due to the Ago2 bound resulting in minimal RISC. Indeed, if the miRNA‐Ago2 complex is present, miRNAs are protected from release or degradation and they are biologically active. Thus, RBCs can act as miRNA carriers for
Elena Perla, Faiza Abbas, Luigia Rossi, Mauro Magnani, Sara Biagiotti   +4 more
wiley   +1 more source

Correction: A comparative analysis of the principal component analysis and entropy weight methods to establish the indexing measurement. [PDF]

PLoS One
PLOS ONE Staff.
europepmc   +1 more source

Characterisation of the role played by ELMO1, GPR141 and the intergenic polymorphism rs918980 in Fuchs' dystrophy in the Indian population

FEBS Open Bio, EarlyView.
This study reports the upregulation of ELMO1 and GPR141 in human Fuchs' endothelial corneal dystrophy (FECD) corneal endothelium and ultraviolet A‐induced FECD mice model. A genetic association of an intergenic single nucleotide polymorphism rs918980 present between both genes is observed with FECD in the Indian population.
Susmita Sharma, Samar Kumar Basak, Sujata Das, Debasmita Pankaj Alone   +3 more
wiley   +1 more source

PANE: fast and reliable ancestral reconstruction on ancient genotype data with non-negative least square and principal component analysis. [PDF]

Genome Biol
de Gennaro L, Molinaro L, Raveane A, Santonastaso F, Saponetti SS, Massi MC, Pagani L, Metspalu M, Hellenthal G, Kivisild T, Ventura M, Montinaro F.   +11 more
europepmc   +1 more source

Automatic Redshift Determination by Use of Principal Component Analysis. I. Fundamentals

, 1998
Karl Glazebrook, Alison Offer, Kathryn Deeley   +2 more
openalex   +1 more source