Results 61 to 70 of about 744,201 (267)
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
FEBS Letters, EarlyView.The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
FEBS Letters, EarlyView.The pyruvate generator, which causes activation of respiration by extra‐mitochondrial Ca2+, is also present and functional in rat brainstem mitochondria, as it is in other brain regions. This finding is confirmed by experiments with a fully reconstituted malate–aspartate shuttle (MAS).
Grazyna Debska‐Vielhaber +7 more
wiley +1 more source
Heartbeat of the sun from principal component analysis and prediction of solar activity on a millenium timescale [PDF]
, 2015 We derive two principal components (PCs) of temporal magnetic field variations over the solar cycles 21-24 from full disk magnetograms covering about 39% of data variance, with σ = 0.67. These PCs are attributed to two main magnetic waves travelling from
Shepherd, Simon J. +10 more
core +1 more source
Contrastive Principal Component Analysis
CoRR, 2017 main body is 10 pages, 9 ...
Abubakar Abid +3 more
openaire +2 more sources
Spherical Principal Component Analysis [PDF]
, 2019 Principal Component Analysis (PCA) is one of the most important methods to handle high dimensional data. However, most of the studies on PCA aim to minimize the loss after projection, which usually measures the Euclidean distance, though in some fields, angle distance is known to be more important and critical for analysis.
Kai Liu 0018 +3 more
openaire +2 more sources
Principal Component Analysis of Volatility Smiles and Skews [PDF]
Several principal component models of volatility smiles and skews have been based on daily changes in implied volatilities, by strike and/or by moneyness.
Carol Alexander
core
Block Principal Component Analysis With Nongreedy l(1)-Norm Maximization
, 2016 Block principal component analysis with l(1)-norm (BPCA-L1) has demonstrated its effectiveness in a lot of visual classification and data mining tasks. However, the greedy strategy for solving the l(1)-norm maximization problem is prone to being struck
Wang, Rong +6 more
core +1 more source
On the multiway principal component analysis
The Annals of StatisticsMultiway data are becoming more and more common. While there are many approaches to extending principal component analysis (PCA) from usual data matrices to multiway arrays, their conceptual differences from the usual PCA, and the methodological implications of such differences remain largely unknown.
Ouyang, Jialin, Yuan, Ming
openaire +3 more sources
FEBS Letters, EarlyView.An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source
Ubiquitination of secretory granules promotes their crinophagic degradation in Drosophila
FEBS Letters, EarlyView.Ubiquitination of secretory granules in Drosophila larval salivary glands is a critical molecular trigger for crinophagy, the lysosomal degradation of unreleased, or low‐quality granules. The E3 ubiquitin ligase Cnot4 is recruited to the surface of secretory granules to induce crinophagy.
Tamás Csizmadia +6 more
wiley +1 more source