Results 121 to 130 of about 26,186,381 (274)

Time History Gaussian Process Regression for Modeling the Dynamics of Ankle Exoskeleton User Comfort

open access: yesAdvanced Robotics Research, EarlyView.
Exoskeletons need to be comfortable, but the perception of comfort may change over time. This study investigated if short‐term time history directly influences comfort. No previous trials’ input features were predictive of comfort. Including the previous trial's comfort score marginally improved model accuracy compared to a model using only the current
Axl Maberry, Bo Cheng, Anne E. Martin
wiley   +1 more source

Chemical Screening Identifies Danofloxacin as a Self‐Renewal Agonist of Embryonic Stem Cells through Alleviation of HDAC1‐Mediated Deacetylation of Tert and Prdm10

open access: yesAdvanced Science, EarlyView.
This study identified Danofloxacin as a novel supporter of the maintenance of mouse embryonic stem cell (ESC) pluripotency. It functions partially by inhibiting HDAC1, which increases specific histone acetylation marks and activates key genes like Tert and Prdm10.
Yan Zhang   +8 more
wiley   +1 more source

CD9+ B Cells Induce T Follicular Helper Cell Apoptosis to Regulate Germinal Center Regression

open access: yesAdvanced Science, EarlyView.
A unique subset of CD9+ B cells regulates germinal center B (GC‐B) cell regression by inducing T follicular helper (Tfh) cell apoptosis through multiple signaling pathways, such as ALCAM‐CD6. FOXP1 plays a key role in GC‐B cell differentiation. These findings clarify mechanisms of GC degeneration and termination and offer potential targets for adenoid ...
Wenjing Liao   +27 more
wiley   +1 more source

Summed Component Analysis for Dimensionality Reduction and Classification [PDF]

open access: yes, 2013
In the area of dimensionality reduction, principal component analysis (PCA) has been used with much success. Other dimensionality reduction techniques have been proposed such as principal feature analysis (PFA) which was developed by Ira Cohen, Qi Tian ...
Ersoy, Okan, Sofolahan, Mopelola
core   +1 more source

Inhibition of IGFBP4 in Granulosa Cells Improves Reproductive Performance and Maintains Fertility With Age via YAP Signaling

open access: yesAdvanced Science, EarlyView.
IGFBP4 is upregulated in granulosa cells of aged ovaries across monkeys, mice, and humans. It inhibits YAP signaling, thereby suppressing cell proliferation and contributing to follicular dysfunction. Deletion of Igfbp4 in granulosa cells enhances ovulatory output, improves hormone profiles, and reproductive performance in aged female mice, suggesting ...
Qianhui Hu   +8 more
wiley   +1 more source

Requirements, Challenges and Implications of Sustainability Reporting Assurance with Principal Component Analysis Method (PCA) [PDF]

open access: yesپژوهش‌های حسابداری و حسابرسی عملیاتی و عملکرد
Corporate responsibility for sustainability issues has attracted much global attention in recent years due to disasters such as pollution and ozone layer depletion.
Ghodratallah Barzegar, masoome kazemi
doaj  

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