Kernel principal component analysis (PCA) control chart for monitoring mixed non-linear variable and attribute quality characteristics. [PDF]
Ahsan M, Mashuri M, Khusna H, Wibawati.
europepmc +1 more source
CORE: Cholesterol Altered Lipid Nanoparticles for Splenic Expression of mRNA Payloads
In this paper researchers introduce CORE LNPs, a new class of lipid nanoparticles engineered to redirect mRNA expression away from the liver and into the spleen, a key immune organ. By combining chemical design with computational tools, they created cholesterol analogs that enable precise spleen‐targeted expression, providing greater applications for ...
Eshan A. Narasipura +4 more
wiley +1 more source
Reproducibility of the principal component analysis (PCA)-based data-driven respiratory gating on texture features in non-small cell lung cancer patients with 18 F-FDG PET/CT. [PDF]
Fukai S +7 more
europepmc +1 more source
Zonated osteochondral assembloid implants are engineered through scaffold‐free spatial assembly of induced pluripotent stem cell (iPSC)‐derived chondrocyte organoids and periosteum‐derived osteogenic organoids. Implanted into full‐thickness rat osteochondral defects, they promote hyaline‐like cartilage repair, support subchondral bone formation with ...
Liuqi Peng +3 more
wiley +1 more source
Assessment of the Efficiency of Chemical and Thermochemical Depolymerization Methods for Lignin Valorization: Principal Component Analysis (PCA) Approach. [PDF]
Younes K +5 more
europepmc +1 more source
Bottom‐Up Programming of Cell States in Cancer Organoids with Defined Synthetic Adhesion Cues
A bottom‐up biomaterial platform is developed to program transcriptomic states in pancreatic cancer organoids by tuning adhesion cues within synthetic matrices. By combining a Design of Experiments framework with multiobjective optimization, matrix compositions are identified that enrich specific cellular programs like EMT.
Ali Nadernezhad +6 more
wiley +1 more source
Requirements, Challenges and Implications of Sustainability Reporting Assurance with Principal Component Analysis Method (PCA) [PDF]
Corporate responsibility for sustainability issues has attracted much global attention in recent years due to disasters such as pollution and ozone layer depletion.
Ghodratallah Barzegar, masoome kazemi
doaj
The Application of Principal Component Analysis (PCA) for the Optimization of the Conditions of Fabrication of Electrospun Nanofibrous Membrane for Desalination and Ion Removal. [PDF]
Younes K +6 more
europepmc +1 more source
A nano‐interception strategy disrupts pathogenic fibroblast–macrophage crosstalk in chronic heart failure. Scalable Prussian blue nanoparticles selectively sequester CCL2 via ultrahigh‐affinity binding, preventing CCR2+ macrophage recruitment and breaking a key fibro‐inflammatory circuit. This approach demonstrates robust efficacy in murine and porcine
Bo Chen +16 more
wiley +1 more source
Low-temperature thermal hydrolysis of sludge prior to anaerobic digestion: Principal component analysis (PCA) of experimental data. [PDF]
Meshref MNA +4 more
europepmc +1 more source

