Results 71 to 80 of about 2,294,043 (337)
FEBS Letters, EarlyView.In this study, we present the structure of AcrIE8.1, a previously uncharacterized anti‐CRISPR protein that inhibits the type I‐E CRISPR‐Cas system. Through a combination of structural and biochemical analyses, we demonstrate that AcrIE8.1 directly binds to the Cas11 subunit of the Cascade complex to inhibit the CRISPR‐Cas system.
Young Woo Kang, Hyun Ho Park
wiley +1 more source
Principal independent component analysis [PDF]
IEEE Transactions on Neural Networks, 1999 Conventional blind signal separation algorithms do not adopt any asymmetric information of the input sources, thus the convergence point of a single output is always unpredictable. However, in most of the applications, we are usually interested in only one or two of the source signals and prior information is almost always available.
J, Luo, B, Hu, X T, Ling, R W, Liu
openaire +2 more sources
Principal Components of Short-term Variability in Venus' UV Albedo
, 2019 We explore the dominant modes of variability in the observed albedo at the cloud tops of Venus using the Akatsuki UVI 283-nm and 365-nm observations, which are sensitive to SO2 and unknown UV absorber distributions respectively, over the period Dec 2016 ...
Imamura, Takeshi +3 more
core +1 more source
An intracellular transporter mitigates the CO2‐induced decline in iron content in Arabidopsis shoots
FEBS Letters, EarlyView.This study identifies a gene encoding a transmembrane protein, MIC, which contributes to the reduction of shoot Fe content observed in plants under elevated CO2. MIC is a putative Fe transporter localized to the Golgi and endosomal compartments. Its post‐translational regulation in roots may represent a potential target for improving plant nutrition ...
Timothy Mozzanino +7 more
wiley +1 more source
Prediction Method of Coal Dust Explosion Flame Propagation Characteristics Based on Principal Component Analysis and BP Neural Network [PDF]
, 2022 Tianqi Liu +4 more
openalex +1 more source
A Cre‐dependent lentiviral vector for neuron subtype‐specific expression of large proteins
FEBS Letters, EarlyView.We designed a versatile and modular lentivector comprising a Cre‐dependent switch and self‐cleaving 2A peptide and tested it for co‐expression of GFP and a 2.8 kb gene of interest (GOI) in mouse cortical parvalbumin (PV+) interneurons and midbrain dopamine (TH+) neurons.
Weixuan Xue +6 more
wiley +1 more source
Using principal component analysis to explore co‐variation of vowels [PDF]
, 2022 Joshua Wilson Black +3 more
openalex +1 more source
FEBS Letters, EarlyView.Anaplastic thyroid cancer (ATC) lacks iodide uptake ability due to MAPK activation increasing the expression of the histone methyltransferase EZH2, which represses thyroid differentiation genes (TDGs) such as the sodium iodide symporter (NIS). Dual inhibition of MAPK (U0126) and EZH2 (EPZ6438/Tazemetostat) reverses this mechanism, thus restoring TDG ...
Diego Claro de Mello +6 more
wiley +1 more source
Technical note: Performance evaluation of volumetric imaging based on motion modeling by principal component analysis [PDF]
, 2022 Suzuka Asano +10 more
openalex +1 more source
By dawn or dusk—how circadian timing rewrites bacterial infection outcomes
FEBS Letters, EarlyView.The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo +2 more
wiley +1 more source