Results 271 to 280 of about 2,259,407 (341)

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

open access: yesFEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj   +3 more
wiley   +1 more source

Exploring Predictors of Bioavailability for a Variety Polyphenols Through Caco-2 Cell Model: Insights from Permeability Studies and Principal Component Analysis

open access: green
Dong-Ho Lee   +8 more
openalex   +1 more source

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

open access: yesFEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid   +3 more
wiley   +1 more source

Predictors of change in dietary patterns determined by principal component analysis in Australians <55 years

open access: green
MG Thorpe (15816605)   +3 more
openalex  

Principal components analysis.

Methods in molecular biology, 2013
Principal components analysis (PCA) is a standard tool in multivariate data analysis to reduce the number of dimensions, while retaining as much as possible of the data's variation. Instead of investigating thousands of original variables, the first few components containing the majority of the data's variation are explored.
Detlef Groth   +3 more
semanticscholar   +4 more sources

Coupled Principal Component Analysis

IEEE Transactions on Neural Networks, 2004
A framework for a class of coupled principal component learning rules is presented. In coupled rules, eigenvectors and eigenvalues of a covariance matrix are simultaneously estimated in coupled equations. Coupled rules can mitigate the stability-speed problem affecting noncoupled learning rules, since the convergence speed in all eigendirections of the
Möller, Ralf, Könies, Axel
openaire   +5 more sources

Directed Principal Component Analysis

Operations Research, 2014
We consider a problem involving estimation of a high-dimensional covariance matrix that is the sum of a diagonal matrix and a low-rank matrix, and making a decision based on the resulting estimate. Such problems arise, for example, in portfolio management, where a common approach employs principal component analysis (PCA) to estimate factors used in ...
Kao, Yi-Hao, Van Roy, Benjamin
openaire   +2 more sources

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