Results 141 to 150 of about 25,782,438 (282)

Mr BMT Achieves Systemic Macrophage Replacement With Preservation of Tissue Homeostasis

Advanced Science, EarlyView.
Microglia replacement by bone marrow transplantation (Mr BMT) enables systemic replacement of tissue‐resident macrophages. Despite persistent macrophage and tissue remodeling across multiple organs, core biological functions and innate immune responses remain preserved, supporting long‐term maintenance of organismal homeostasis and the therapeutic ...
Yufei Xu, Miaozhan Zou, Yunshang Bai, Yang He, Zhihao Jin, Baozhi Yang, Jinjin Du, Pei Ouyang, Yuanyuan Cai, Yuheng Zhang, Bingying Du, Chengcheng Ge, Jian‐an Gong, Xiaoyu Li, Yuanyi Zheng, Jing Ding, Bo Peng, Yanxia Rao   +17 more
wiley   +1 more source

Uncovering eutrophication dynamics using PCA-driven spatiotemporal assessment of lake water quality indicators. [PDF]

Environ Monit Assess
Timilshina S, Sharma S, Paneru A, Davis M, Mathis T.   +4 more
europepmc   +1 more source

The Use of Features Extracted from Noisy Samples for Image Restoration Purposes [PDF]

An important feature of neural networks is the ability they have to learn from their environment, and, through learning to improve performance in some sense.
Panayiotis VLAMOS, Catalina COCIANU, Luminita STATE   +2 more
core  

NeuroSuite for Long‐Term Functional and Structural Studies of Air‐Liquid Interface Cerebral Organoids

Advanced Science, EarlyView.
NeuroSuite provides a modular hardware‐software platform integrating Neuroweb and NeuroMaps to enable long‐term, in situ electrophysiological interrogation of air–liquid interface organoid slices while preserving tissue architecture. Its components can be used together or independently to capture real‐time activity, spatial network dynamics, and ...
Belquis Haider, Sagnik Middya, Daniel J. Lloyd‐Davies‐Sánchez, Nino F. Läubli, Sulay Vora, Jakob Träuble, Rohan N. Krajeski, Yuqing Feng, Daniel Duncko, Josiah S. Riley, Rubén Ruiz‐Mateos Serrano, Ole Paulsen, Madeline A. Lancaster, George G. Malliaras, Gabriele S. Kaminski Schierle   +14 more
wiley   +1 more source

Principal Components Analysis Relates Hippocampal Trisynaptic Circuit to Vividness of Visual Mental Imagery. [PDF]

Brain Behav
Marks DF.
europepmc   +1 more source

A principal components analysis of the UK term structure and the influence of fiscal policy [PDF]

This study examines the use of principal component techniques in analysing term structures of interest rates. It employs original methods of estimating B-Spline models with endogenous knot positions and applies the method of Dierckx (1981) to generate ...
Egginton, D. M. (Donald Michael)
core  

Innate Immunocompetent hiPSC‐Derived Neurospheroids Capture Early CNS Responses to rAAV

Advanced Science, EarlyView.
Knowledge of human CNS immune responses to AAV‐based gene therapies remains limited due to the lack of immune‐competent human models. Here, a hiPSC‐derived 3D neuroimmune platform integrating neurospheroids and microglia is established using stirred‐tank bioreactors.
Catarina M. Gomes, Gabriela Silva, Mafalda Aleixo, Marta Gomes, Daniel Simão, Stephan J. Holtkamp, Diana D. Lobo, Pradeep Harish, Rosalind Jenkins, Lekh N. Dahal, Rui J. Nobre, Luís de Pereira de Almeida, Mark Trautwein, Paula M. Alves, Catarina Brito   +14 more
wiley   +1 more source

Metabolic phenotype dimensions and longitudinal renal function in type 2 diabetes: a principal component analysis-based approach with UACR integration. [PDF]

Front Endocrinol (Lausanne)
Mei C, Li Y, Ma H, Li X, Jiang S.
europepmc   +1 more source

Engineering Immunoregenerative Therapy via an Immunomodulatory Binary Pharmacology Hydrogel Depot for Prolonged Allograft Survival

Advanced Science, EarlyView.
An immunomodulatory hydrogel (iGEL) forms spontaneously upon subcutaneous injection, acting as a tissue‐adhesive depot. It releases anti‐rejection and regenerative agents in response to inflammation, suppressing T‐cell activity, promoting vascular repair, and restoring allograft function without systemic immunosuppression.
Ning Wang, Ruiqi Sun, Yang Fu, Zhonghan Wu, Xinyu Tong, Hong Tang, Wentao Zhao, Zhi Liang, Jintao Zheng, Yanan Guan, Ke Zhou, Penghong Song, Shusen Zheng, Hangxiang Wang, Haiyang Xie   +14 more
wiley   +1 more source

Development of a Multimodal Machine Learning Model for Predicting Second Osteoporotic Vertebral Compression Fractures. [PDF]

Yonsei Med J
Cho H, Joo MK, Cho PG, Kim SH, Noh SH.
europepmc   +1 more source