Results 71 to 80 of about 4,751,424 (317)
Molecular Oncology, EarlyView.Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard +5 more
wiley +1 more source
ON CLASSES OF MODULES CLOSED UNDER INJECTIVE HULLS AND ARTINIAN PRINCIPAL IDEAL RINGS
, 2014 In this work we consider some classes of modules closed under certain closure properties such as being closed under taking submodules, quotients, injective hulls and direct sums.
Alejandro Alvarado-Garćıa +3 more
semanticscholar +1 more source
Factoring formal power series over principal ideal domains [PDF]
, 2011 We provide an irreducibility test and factoring algorithm (with some qualificiations) for formal power series in the unique factorization domain R((X)), where R is any principal ideal domain.
J. Elliott
semanticscholar +1 more source
Molecular Oncology, EarlyView.CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir +12 more
wiley +1 more source
Explicit decomposition of a rational prime in a cubic field
International Journal of Mathematics and Mathematical Sciences, 2006 We give the explicit decomposition of the principal ideal 〈p〉 (p prime) in a cubic field.
Saban Alaca +2 more
doaj +1 more source
Some Properties of the Intersection Graph for Finite Commutative Principal Ideal Rings
, 2014 Let R be a commutative finite principal ideal ring with unity, and let G(R) be the simple graph consisting of nontrivial proper ideals of R as vertices such that two vertices I and J are adjacent if they have nonzero intersection.
E. A. Osba +2 more
semanticscholar +1 more source
The Structure of Finite Local Principal Ideal Rings [PDF]
, 2011 A ring R is called a principal ideal ring (PIR), if each ideal of R is a principal ideal. A local ring (R, 𝔪) is an artinian PIR if and only if its maximal ideal 𝔪 is principal and has finite nilpotency index.
Tongsuo Wu, Houyi Yu, D. Lu
semanticscholar +1 more source
Molecular Oncology, EarlyView.A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He +8 more
wiley +1 more source
Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA
Molecular Oncology, EarlyView.Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson +2 more
wiley +1 more source
Molecular Oncology, EarlyView.Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz +15 more
wiley +1 more source