Results 81 to 90 of about 397,514 (346)
Molecular Oncology, EarlyView.Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz +15 more
wiley +1 more source
, 2020 Consider rectangular matrices over a commutative ring R. Assume the ideal of maximal minors factorizes, I_m(A)=J_1*J_2. When is A left-right equivalent to a block-diagonal matrix? (When does the module/sheaf Coker(A) decompose as the corresponding direct
Kerner, Dmitry, Vinnikov, Victor
core
Molecular Oncology, EarlyView.The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg +43 more
wiley +1 more source
Molecular Oncology, EarlyView.This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris +10 more
wiley +1 more source
Subrings of I-rings and S-rings
International Journal of Mathematics and Mathematical Sciences, 1997 Let R be a non-commutative associative ring with unity 1≠0, a left R-module is said to satisfy property (I) (resp. (S)) if every injective (resp. surjective) endomorphism of M is an automorphism of M.
Mamadou Sanghare
doaj +1 more source
Noncrossed Product Matrix Subrings and Ideals of Graded Rings
, 2009 We show that if a groupoid graded ring has a certain nonzero ideal property and the principal component of the ring is commutative, then the intersection of a nonzero twosided ideal of the ring with the commutant of the principal component of the ring is
Lundström, Patrik, Öinert, Johan
core
Some Properties of the Intersection Graph for Finite Commutative Principal Ideal Rings
, 2014 Let R be a commutative finite principal ideal ring with unity, and let G(R) be the simple graph consisting of nontrivial proper ideals of R as vertices such that two vertices I and J are adjacent if they have nonzero intersection.
E. A. Osba +2 more
semanticscholar +1 more source
Tumor mutational burden as a determinant of metastatic dissemination patterns
Molecular Oncology, EarlyView.This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal +4 more
wiley +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
On a principal ideal domain that is not a Euclidean domain
, 2013 The ring Z[ √−19 2 ] is usually given as a first example of a principal ideal domain (PID) that is not a Euclidean domain. This paper gives an elementary and more direct proof that Z[ √−19 2 ] is indeed a PID.
Conan Wong
semanticscholar +1 more source