Results 121 to 130 of about 6,258,593 (311)

Investigation of the solution of a boundary value problem with variable coefficients whose principal part is the Cauchy–Riemann equation

open access: yesҚарағанды университетінің хабаршысы. Математика сериясы
This study is devoted to obtaining an analytical expression for the solution of a non-local boundary value problem for a linear inhomogeneous differential equation with variable coefficients, which principle part is the Cauchy–Riemann equation.
M. Rasulov, N. Aliyev, B. Sinsoysal
doaj   +1 more source

RNA‐related functions of BRCA2 in transcription, replication, and genome stability

open access: yesFEBS Letters, EarlyView.
Beyond its role in homologous recombination, BRCA2 regulates R‐loop homeostasis, DNA–RNA hybrid resolution, RNA polymerase II dynamics, and transcriptional activation. Disruption of any of these functions can contribute to genome instability, inflammatory signaling, and tumorigenesis. BRCA2 is a central tumor suppressor protein best known for its roles
Lucia Alvaro‐Aranda   +2 more
wiley   +1 more source

Time series forecasting by principal covariate regression. [PDF]

open access: yes
This paper is concerned with time series forecasting in the presence of a large numberof predictors. The results are of interest, for instance, in macroeconomic and financialforecasting where often many potential predictor variables are available.
Dijk, D.J.C. van   +2 more
core  

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

open access: yesFEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise   +5 more
wiley   +1 more source

Principal-Agent Problem with Minimum Performance Insurance [PDF]

open access: yes
A minimum performance insurance in the Principal-Agent problem is wealth reducing to the principal. This result points to further inefficiencies in mandatory individual Pension Funds' contracts, particularly the one established in the 1993's 100th Law in
Juan Manuel Julio
core  

Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein

open access: yesFEBS Letters, EarlyView.
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux   +7 more
wiley   +1 more source

A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma

open access: yesFEBS Letters, EarlyView.
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos   +9 more
wiley   +1 more source

Control and information in a dynamic multiple agent model. [PDF]

open access: yes
he controllability principle says that an individual should be rewarded on the basis of what he controls. This paper studies this principle from a principal agent point of view.
Pauwels, W., Roodhooft, Filip
core  

The ubiquitin system in normal and infected germinal center B cells

open access: yesFEBS Letters, EarlyView.
The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis   +2 more
wiley   +1 more source

On principal solutions of linear differential equations [PDF]

open access: yesProceedings of the American Mathematical Society, 1968
openaire   +1 more source

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