Results 151 to 160 of about 191,225 (267)

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

RISE : evaluation of principals in Indiana

, 2015
Effective school principals are needed to lead efforts towards quality educational opportunities for all students. Evaluation practices that foster principal effectiveness are critically important in improving professional practices.
Andrews, Kelly Ann
core  

Leading beyond the Job Description: Investigating the Association between Principals' Leadership Styles and Teachers' Organizational Citizenship Behaviors in North Wollo Secondary Schools. [PDF]

F1000Res
Belay Y, Tafere M.
europepmc   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Perceived principals' aesthetic leadership and teacher professional development: the roles of aesthetic experience and psychological empowerment among Chinese high school teachers. [PDF]

Front Psychol
Yin Z, Chang Y, Qian F, Lin W, Fang K.
europepmc   +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

Molecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera, Laura Vela‐Martín, Pablo Fernández‐Navarro, José Luis López‐Lorenzo, Javier Cornago, Pilar Llamas, Eduardo Pérez‐Gómez, José Luis Marín‐Rubio, Manuel Fresno, Javier Santos, José Fernández‐Piqueras, María Villa‐Morales   +11 more
wiley   +1 more source

The influence of reading nationally circulated scholarly educational literature as manifested in the curricular leadership performance of middle school principals

, 1990
This study was designed to investigate whether and to what extent middle school principals are reading nationally circulated scholarly educational literature that calls for curriculum change.
Savidge, David B.
core  

School principals' COVID-19 health literacy and its association with mental health: international findings from 11 countries in Europe and Asia. [PDF]

Health Promot Int
Meyer M, Dadaczynski K, Messer M, Kristensen RM, Simovska V, Lagiou A, Sakellari E, Amoah PA, Lau SSS, Leung AYM, Bonaccorsi G, Lorini C, Velasco V, Duplaga M, Leksy K, Coman MA, Sandmeier A, Lin CY, Van Duong T, Özturk FÖ, Soylar P, Marchant E, Okan O.   +22 more
europepmc   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

Utilization of Artificial Intelligence to support administrative decision-making in special education institutions in Saudi Arabia: perceptions of principals, supervisors, and teachers. [PDF]

Front Artif Intell
Alsuhaymi A, Eltantawy MM.
europepmc   +1 more source