Results 71 to 80 of about 1,776,399 (318)

Darwin's Principle of Divergence [PDF]

open access: yes, 2004
Darwin's famous book, is not an easy book for the reader. Especially, the central part of his doctrine addressing the problem of how a small difference between varieties of a single species may become larger and larger and become a large difference ...
Uchii, Soshichi
core  

Cost Recovery for Water Services and the Polluter Pays Principle [PDF]

open access: yes, 2009
This paper considers the general rationale for cost recovery pricing in respect of water services and examines the specific provision that is made for this, and related obligations, in Article 9 of the European Community Water Framework Directive ...
Howarth, William
core   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome

open access: yesFEBS Letters, EarlyView.
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley   +1 more source

PRINSIP PENGGEMBALAAN DALAM MAZMUR 23

open access: yesManna Rafflesia, 2020
There are many writings that deal with shepherding. In this article we discuss" Shepherding Principles "based on the perspective of Psalm 23. The psalmist stresses the importance of understanding the shepherding principle. In this discussion will explain
Waharman Waharman
doaj   +1 more source

The principles of Kemalism

open access: yesMilletleraras, 1980
Mustafa Kemal Atatürk (1881- 1938) is not generallyknown as a "builder" of theories. it was his deliberatechoice not to leave behind an "inflexible doctrine". Hewanted his teachings to be dynamic views suiting the needto become contemporary in every way. Ideologies, no doubt.play a role in all regimes.
openaire   +2 more sources

Cell geometry and membrane protein crowding constrain Escherichia coli growth rate, overflow metabolism, respiration, and maintenance energy

open access: yesFEBS Letters, EarlyView.
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson   +6 more
wiley   +1 more source

Is it the Principal Principle that Implies the Principle of Indifference? [PDF]

open access: yes, 2017
Hawthorne et al. (Br J Philos Sci, http://bjps.oxfordjournals.org/lookup/doi/10.1093/bjps/axv030) argue that the Principal Principle implies a version of the Principle of Indifference. We show that what the Authors take to be the Principle of Indifference can be obtained without invoking anything which would seem to be related to the Principal ...
Gyenis, Balázs, Wroński, Leszek
openaire   +2 more sources

Phosphoinositides and inositol phosphates as molecular glues

open access: yesFEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry   +9 more
wiley   +1 more source

Non-discrimination in the draft of the Serbian Civil Code [PDF]

open access: yesZbornik Radova: Pravni Fakultet u Novom Sadu, 2018
The draft of the Serbian Civil Code facilitates the combat against discrimination in several ways. It enables the impact of non-discrimination norms in the civil law relations according to each of three theoretical models of appllication od human rights ...
Rašević Živorad M.
doaj  

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