Results 121 to 130 of about 1,776,399 (318)

Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis

open access: yesMolecular Oncology, EarlyView.
This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht   +3 more
wiley   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

open access: yesMolecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim   +3 more
wiley   +1 more source

Corporations Law : In Principle

open access: yes, 2009
8th ed.Tony Ciro and Christopher Symes1. History, administration and reform -- 2. Types of companies -- 3. Registration -- 4. Consequences of registration -- 5. Internal rules -- 6. Management of companies -- 7.
Symes, C., Ciro, T.
core  

On the Galoisian Structure of Heisenberg Indeterminacy Principle [PDF]

open access: yes, 2013
We revisit Heisenberg indeterminacy principle in the light of the Galois-Grothendieck theory for the case of finite abelian Galois extensions. In this restricted framework, the Galois-Grothendieck duality between finite K-algebras split by a Galois ...
Catren, Gabriel, Page, Julien
core  

From tumor‐centric to ecosystem‐based hypotheses in brain tumor research and care

open access: yesMolecular Oncology, EarlyView.
Primary brain tumors, whether in adults or children, present a major challenge because of their dramatic prognosis and the ongoing lack of efficient therapeutic approaches. In recent years, a shift has occurred from tumor‐centric concepts to a more holistic view of these tumors as dynamic ecosystems.
Julie Gavard   +8 more
wiley   +1 more source

Principle of Uncertain Future [PDF]

open access: yes
The principle of uncertain future: the probability of a future event contains a degree of (hidden) uncertainty. As a result, this uncertainty (in a sense, similar to vibrations, fluctuations) pushes the probability value back from the bounds to the ...
Alexander Harin
core  

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

open access: yesFEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj   +3 more
wiley   +1 more source

Enhancing the implementation of the Aboriginal and Torres Strait Islander Child Placement Principle: policy and practice considerations [PDF]

open access: yes, 2015
Overview The Aboriginal and Torres Strait Islander Child Placement Principle ("the Principle") was developed in recognition of the devastating effects of forced separation of Indigenous children from families, communities and culture.
Marie Iannos   +4 more
core  

Meşşâî İslam Filozoflarında ‘Tabiat’ Kavramı

open access: yesULUM, 2018
Bu çalışmada “tabiat” kavramının sözlük ve terim anlamı analiz edilmiş ve ona ilişkin bazı Meşşâî İslam filozoflarının görüşlerine yer verilmiştir.
Nuri Adıgüzel
doaj  

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

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