Results 121 to 130 of about 3,653,860 (344)
Molecular Oncology, EarlyView.Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur +11 more
wiley +1 more source
BANKING ETHICS: MAIN CONCEPTIONS AND PROBLEMS [PDF]
Annals of the University of Petrosani: Economics, 2014 Banking ethics is a specialized set of ethical standards and rules that should be followed in the activities of financial institutions and employees of the banking sector.
VALENTINA FETINIUC, IVAN LUCHIAN
doaj
MEANS OF PRESERVING NATIONAL VALUES IN EDUCATION, PATRIOTISM, AND UPBRINGING [PDF]
Vestnik Issyk-Kulʹskogo universitetaThis scientific and methodological work analyzes in detail the ways, of techniques and substantive features of patriotic education of elementary school students through artistic works.
Isakova S. T. +2 more
doaj +1 more source
Corporations Law : In Principle
, 2009 8th ed.Tony Ciro and Christopher Symes1. History, administration and reform -- 2. Types of companies -- 3. Registration -- 4. Consequences of registration -- 5. Internal rules -- 6. Management of companies -- 7.
Symes, C., Ciro, T.
core
Translating whole‐genome doubling into precision medicine in cancer
Molecular Oncology, EarlyView.Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley +1 more source
A process of transformation of institucional’nykh terms is in the enterprise environment of Russia
Ученые записки Российской академии предпринимательства, 2021 In the article the process of transformation of changes is examined in development of enterprise environment in Russia. Basis ofenterprise environment is freedom of businessman and any unworked out actions from the side of supervisory organs can result ...
A. M. Chernopyatov
doaj
Molecular Oncology, EarlyView.Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley +1 more source
Molecular Oncology, EarlyView.This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu +3 more
wiley +1 more source
The principle of goodness and reality situating a fundamental ethical principle [PDF]
, 2005 This paper describes an ethical theory provisionally called the Principle of Goodness. Before doing so, however, it is necessary to discuss the nature of human beliefs in general, in order to correctly situate the theory.
House, Ron
core +1 more source
Spatial biology in cancer epigenetics
Molecular Oncology, EarlyView.Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley +1 more source